A Compound isolated from Rumex japonicus induces early growth response gene-1 expression

被引：2
|
作者：
Geunhyeong Jo
Soon Young Shin
Younggiu Lee
Jiye Hyun
Kwang Sik Dong
Jun Cheol Park
Hyun Su Kim
Young Han Lee
Yoongho Lim
机构：
[1] Konkuk University,Division of Bioscience and Biotechnology, BMIC
[2] Konkuk University,Department of Biomedical Science and Technology, RCTC, SMART Institute of Advanced Biomedical Science
[3] National Institute of Animal Science,Rural Development Administration
[4] International University of Korea,Department of Pharmaceutical Engineering
来源：
Journal of the Korean Society for Applied Biological Chemistry | 2011年 / 54卷
关键词：
clonogenic assay; early growth response-1 gene; flavonoid; parietin;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
A compound was isolated from the root of Rumex japonicus. Based on spectroscopic data including nuclear magnetic resonance spectroscopy and mass spectrometry, the chemical structure of the compound was determined to be 1,8-dihydroxy-3-methoxy-6-methylanthracene-9,10-dione. The compound exhibits antitumor activity due to inhibition of clonogenicity and induction of tumor suppressor early growth response gene-1 in HCT116 colon cancer cells.
引用
收藏
页码：637 / 643
页数：6
相关论文
共 50 条
  • [1] A Compound Isolated from Rumex japonicus Induces Early Growth Response Gene-I Expression
    Jo, Geunhyeong
    Shin, Soon Young
    Lee, Younggiu
    Hyun, Jiye
    Dong, Kwang Sik
    Park, Jun Cheol
    Kim, Hyun Su
    Lee, Young Han
    Lim, Yoongho
    JOURNAL OF THE KOREAN SOCIETY FOR APPLIED BIOLOGICAL CHEMISTRY, 2011, 54 (04): : 637 - 643
  • [2] A Compound isolated from Rumex japonicus induces apoptosis in heLa cells
    Yeonjoong Yong
    Soon Young Shin
    Younggiu Lee
    Sang Ho Kim
    Young Han Lee
    Yoongho Lim
    Journal of the Korean Society for Applied Biological Chemistry, 2010, 53 : 657 - 660
  • [3] A Compound Isolated from Rumex japonicus Induces Apoptosis in HeLa Cells
    Yong, Yeonjoong
    Shin, Soon Young
    Lee, Younggiu
    Kim, Sang Ho
    Lee, Young Han
    Lim, Yoongho
    JOURNAL OF THE KOREAN SOCIETY FOR APPLIED BIOLOGICAL CHEMISTRY, 2010, 53 (05): : 657 - 660
  • [4] Early growth response gene-1 expression induces epidermal growth factor receptor expression during hypoxia
    Johnson, AC
    Nishi, KH
    Wilson, MA
    Nishi, H
    FASEB JOURNAL, 2002, 16 (04): : A63 - A63
  • [5] Expression of early growth response gene-1 in precancerous lesions of gastric cancer
    Park, Seon-Young
    Kim, Ji-Young
    Lee, Su-Mi
    Chung, Jin Ook
    Lee, Kyung-Hwa
    Jun, Chung-Hwan
    Park, Chang-Hwan
    Kim, Hyun-Soo
    Choi, Sung-Kyu
    Rew, Jong-Sun
    Jung, Young-Do
    Lee, Yong Han
    ONCOLOGY LETTERS, 2016, 12 (04) : 2710 - 2715
  • [6] Early growth response gene-1 regulates the expression of the rat luteinizing hormone receptor gene
    Yoshino, M
    Mizutani, T
    Yamada, K
    Tsuchiya, M
    Minegishi, T
    Yazawa, T
    Kawata, H
    Sekiguchi, T
    Kajitani, T
    Miyamoto, K
    BIOLOGY OF REPRODUCTION, 2002, 66 (06) : 1813 - 1819
  • [7] TNF-α induces early growth response gene-1 expression via ERK1/2 activation in endothelial cells
    Yanli Cao
    Jin Zhang
    Xin Meng
    Difei Wang
    Acta Diabetologica, 2013, 50 : 27 - 31
  • [8] TNF-α induces early growth response gene-1 expression via ERK1/2 activation in endothelial cells
    Cao, Yanli
    Zhang, Jin
    Meng, Xin
    Wang, Difei
    ACTA DIABETOLOGICA, 2013, 50 (01) : 27 - 31
  • [9] IN-SITU EXPRESSION OF THE EARLY GROWTH-RESPONSE GENE-1 DURING MURINE NEPHROGENESIS
    RACKLEY, RR
    KESSLER, PM
    CAMPBELL, C
    WILLIAMS, BRG
    JOURNAL OF UROLOGY, 1995, 154 (02): : 700 - 705
  • [10] DOCA and TGF-β Induce Early Growth Response Gene-1 (Egr-1) Expression
    Friedrich, Bjoern
    Janessa, Andrea
    Artunc, Ferruh
    Aicher, Wilhelm Karl
    Mueller, Gerhard Anton
    Lang, Florian
    Risler, Teut
    Alexander, Dorothea
    CELLULAR PHYSIOLOGY AND BIOCHEMISTRY, 2008, 22 (5-6) : 465 - 474
12345