IL-17A-mediated mitochondrial dysfunction induces pyroptosis in colorectal cancer cells and promotes CD8 + T-cell tumour infiltration

被引:0
|
作者
Wen-Qing Feng
Yu-Chen Zhang
Zhuo-Qing Xu
Su-Yue Yu
Jian-ting Huo
Abudumaimaitijiang Tuersun
Min-Hua Zheng
Jing-Kun Zhao
Ya-Ping Zong
Ai-Guo Lu
机构
[1] Ruijin Hospital,Department of General Surgery, Shanghai Minimally Invasive Surgery Center
[2] Shanghai Jiao Tong University School of Medicine,undefined
关键词
IL-17A; Colorectal cancer; Mitochondrial dysfunction; Pyroptosis; CD8 + T;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
相关论文
共 50 条
  • [41] CD8 T cell-mediated killing of Cryptococcus neoformans requires granulysin and is dependent on CD4 T cells and IL-15
    Ma, LL
    Spurrell, JCL
    Wang, JF
    Neely, GG
    Epelman, S
    Krensky, AM
    Mody, CH
    JOURNAL OF IMMUNOLOGY, 2002, 169 (10): : 5787 - 5795
  • [42] IL-7 induces clathrin-mediated endocytosis of CD127 and subsequent degradation by the proteasome in primary human CD8 T cells
    Faller, Elliott M.
    Ghazawi, Feras M.
    Cavar, Marko
    MacPherson, Paul A.
    IMMUNOLOGY AND CELL BIOLOGY, 2016, 94 (02): : 196 - 207
  • [43] Cytokine-induced IL-10-secreting CD8 T cells represent a phenotypically distinct suppressor T-cell lineage
    Noble, A
    Giorgini, A
    Leggat, JA
    BLOOD, 2006, 107 (11) : 4475 - 4483
  • [44] Pyrimethamine inhibits cell growth by inducing cell senescence and boosting CD8+ T-cell mediated cytotoxicity in colorectal cancer
    Haiyan Dong
    Limei Hu
    Weiqian Li
    Mengchen Shi
    Lingyuan He
    Chen Wang
    Yijia Hu
    Huihui Wang
    Chuangyu Wen
    Huanliang Liu
    Xiangling Yang
    Molecular Biology Reports, 2022, 49 : 4281 - 4292
  • [45] Pyrimethamine inhibits cell growth by inducing cell senescence and boosting CD8+ T-cell mediated cytotoxicity in colorectal cancer
    Dong, Haiyan
    Hu, Limei
    Li, Weiqian
    Shi, Mengchen
    He, Lingyuan
    Wang, Chen
    Hu, Yijia
    Wang, Huihui
    Wen, Chuangyu
    Liu, Huanliang
    Yang, Xiangling
    MOLECULAR BIOLOGY REPORTS, 2022, 49 (06) : 4281 - 4292
  • [46] Overcoming IL-17 Producing CD8 T Cell (T17) Mediated Resistance to Tolerance by Targeting the Novel TIM-1 T Cell Differentiation Pathway.
    Yuan, Xueli
    Ansari, M. Javeed
    D'Addio, Francesca
    Paez-Cortez, Jesus
    Zhao, Xiaozhi
    Schmitt-Knosalla, Isabela
    Donnarumma, Michela
    Boenisch, Olaf
    Popoola, Joyce
    Clarkson, Michael R.
    Yagita, Hideo
    Akiba, Hisaya
    Iacomini, John
    Turka, Laurence A.
    Glimcher, Laurie
    Sayegh, Mohamed H.
    AMERICAN JOURNAL OF TRANSPLANTATION, 2009, 9 : 245 - 245
  • [47] Phenotype analysis of lymphoid cells in Marek's disease of CD4(+) or CD8(+) T-cell-deficient chickens: occurrence of double negative T-cell tumour
    Okada, K
    Tanaka, Y
    Murakami, K
    Chiba, S
    Morimura, T
    Hattori, M
    Goryo, M
    Onuma, M
    AVIAN PATHOLOGY, 1997, 26 (03) : 525 - 534
  • [48] Cooperative action of CD8 T lymphocytes and natural killer cells controls tumour growth under conditions of restricted T-cell receptor diversity
    Shanker, Anil
    Buferne, Michel
    Schmitt-Verhulst, Anne-Marie
    IMMUNOLOGY, 2010, 129 (01) : 41 - 54
  • [49] Induction of antigen-specific CD4- and CD8-mediated T-Cell responses by fusions of autologous dendritic cells and metastatic colorectal cancer cells
    Koido, S
    Hara, E
    Torii, A
    Homma, S
    Toyama, Y
    Kawahara, H
    Ogawa, M
    Watanabe, M
    Yanaga, K
    Fujise, K
    Gong, JL
    Toda, G
    INTERNATIONAL JOURNAL OF CANCER, 2005, 117 (04) : 587 - 595
  • [50] IL-23 Promotes the Production of IL-17 by Antigen-Specific CD8 T Cells in the Absence of IL-12 and Type-I Interferons
    Curtis, Meredith M.
    Way, Sing Sing
    Wilson, Christopher B.
    JOURNAL OF IMMUNOLOGY, 2009, 183 (01): : 381 - 387