IL-17A-mediated mitochondrial dysfunction induces pyroptosis in colorectal cancer cells and promotes CD8 + T-cell tumour infiltration

被引：0
|
作者：
Wen-Qing Feng
Yu-Chen Zhang
Zhuo-Qing Xu
Su-Yue Yu
Jian-ting Huo
Abudumaimaitijiang Tuersun
Min-Hua Zheng
Jing-Kun Zhao
Ya-Ping Zong
Ai-Guo Lu
机构：
[1] Ruijin Hospital,Department of General Surgery, Shanghai Minimally Invasive Surgery Center
[2] Shanghai Jiao Tong University School of Medicine,undefined
来源：
Journal of Translational Medicine | / 21卷
关键词：
IL-17A; Colorectal cancer; Mitochondrial dysfunction; Pyroptosis; CD8 + T;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
相关论文
共 50 条
  • [31] The cholera toxin B subunit induces trained immunity in dendritic cells and promotes CD8 T cell antitumor immunity
    Tepale-Segura, Araceli
    Gajon, Julian A.
    Munoz-Cruz, Samira
    Castro-Escamilla, Octavio
    Bonifaz, Laura C.
    FRONTIERS IN IMMUNOLOGY, 2024, 15
  • [32] Endostatin induces normalization of blood vessels in colorectal cancer and promotes infiltration of CD8+T cells to improve anti-PD-L1 immunotherapy
    Chu, Xiao-Dong
    Bao, Hui
    Lin, Yu-Jian
    Chen, Ruo-Xi
    Zhang, Yi-Ran
    Huang, Ting
    He, Jia-Shuai
    Huangfu, Shu-Chen
    Pan, Yun-Long
    Ding, Hui
    FRONTIERS IN IMMUNOLOGY, 2022, 13
  • [33] CD8 T-CELL INFILTRATION AND TUMOR IL-7R EXPRESSION ARE INDEPENDENT PROGNOSTIC FACTORS IN EPITHELIOID MALIGNANT PLEURAL MESOTHELIOMA
    Ujiie, Hideki
    Buitrago, Daniel
    Nitadori, Junichi
    Kadota, Kyuichi
    Krug, Lee M.
    Travis, William D.
    Rusch, Valerie W.
    Sadelain, Michel
    Adusumilli, Prasad S.
    JOURNAL OF THORACIC ONCOLOGY, 2013, 8 : S223 - S224
  • [34] Cancer cell-intrinsic STING is associated with CD8 + T-cell infiltration and might serve as a potential immunotherapeutic target in hepatocellular carcinoma
    Y. Zhang
    Q. Zhai
    X. Feng
    D. Chen
    Y. Lu
    J. Hu
    H. Xie
    L. Zhou
    J. Wu
    S. Zheng
    Clinical and Translational Oncology, 2021, 23 : 1314 - 1324
  • [35] Follicular regulatory T cells infiltrated the ovarian carcinoma and resulted in CD8 T cell dysfunction dependent on IL-10 pathway
    Li, Li
    Ma, Yan
    Xu, Yuan
    INTERNATIONAL IMMUNOPHARMACOLOGY, 2019, 68 : 81 - 87
  • [36] CD8 T-cells in psoriatic arthritis synovium appear antigen driven with a non antigen specific CD4 T-cell infiltration.
    Curran, S
    Winchester, R
    Costello, P
    Peterson, K
    Sarosy, J
    Bresnihan, B
    FitzGerald, O
    ARTHRITIS AND RHEUMATISM, 1998, 41 (09): : S346 - S346
  • [37] Transregulation of memory CD8 T-cell proliferation by IL-15Rα+ bone marrow-derived cells
    Schluns, KS
    Klonowski, KD
    Lefrançois, L
    BLOOD, 2004, 103 (03) : 988 - 994
  • [38] Pan-Cancer Immunogenomic Perspective on the Tumor Microenvironment Based on PD-L1 and CD8 T-Cell Infiltration
    Ock, Chan-Young
    Keam, Bhumsuk
    Kim, Sehui
    Lee, Ju-Seog
    Kim, Miso
    Kim, Tae Min
    Jeon, Yoon Kyung
    Kim, Dong-Wan
    Chung, Doo Hyun
    Heo, Dae Seog
    CLINICAL CANCER RESEARCH, 2016, 22 (09) : 2261 - 2270
  • [39] Depletion of regulatory T cells in tumors with an anti-CD25 immunotoxin induces CD8 T cell-mediated systemic antitumor immunity
    Onda, Masanori
    Kobayashi, Kazuto
    Pastan, Ira
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2019, 116 (10) : 4575 - 4582
  • [40] Targeting NKG2A to boost anti-tumor CD8 T-cell responses in human colorectal cancer
    Ducoin, Kathleen
    Oger, Romain
    Mutala, Linda Bilonda
    Deleine, Cecile
    Jouand, Nicolas
    Desfrancois, Juliette
    Podevin, Juliette
    Duchalais, Emilie
    Cruard, Jonathan
    Benlalam, Houssem
    Labarriere, Nathalie
    Bossard, Celine
    Jarry, Anne
    Gervois-Segain, Nadine
    ONCOIMMUNOLOGY, 2022, 11 (01):
12345