IL-17A-mediated mitochondrial dysfunction induces pyroptosis in colorectal cancer cells and promotes CD8 + T-cell tumour infiltration

被引：0
|
作者：
Wen-Qing Feng
Yu-Chen Zhang
Zhuo-Qing Xu
Su-Yue Yu
Jian-ting Huo
Abudumaimaitijiang Tuersun
Min-Hua Zheng
Jing-Kun Zhao
Ya-Ping Zong
Ai-Guo Lu
机构：
[1] Ruijin Hospital,Department of General Surgery, Shanghai Minimally Invasive Surgery Center
[2] Shanghai Jiao Tong University School of Medicine,undefined
来源：
Journal of Translational Medicine | / 21卷
关键词：
IL-17A; Colorectal cancer; Mitochondrial dysfunction; Pyroptosis; CD8 + T;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
相关论文
共 50 条
  • [1] IL-17A-mediated mitochondrial dysfunction induces pyroptosis in colorectal cancer cells and promotes CD8+T-cell tumour infiltration
    Feng, Wen-Qing
    Zhang, Yu-Chen
    Xu, Zhuo-Qing
    Yu, Su-Yue
    Huo, Jian-ting
    Tuersun, Abudumaimaitijiang
    Zheng, Min-Hua
    Zhao, Jing-Kun
    Zong, Ya-Ping
    Lu, Ai-Guo
    JOURNAL OF TRANSLATIONAL MEDICINE, 2023, 21 (01)
  • [2] IL-2 consumption by highly activated CD8 T cells induces regulatory T-cell dysfunction in patients with hemophagocytic lymphohistiocytosis
    Humblet-Baron, Stephanie
    Franckaert, Dean
    Dooley, James
    Bornschein, Simon
    Cauwe, Benedicte
    Schonefeldt, Susann
    Bossuyt, Xavier
    Matthys, Patrick
    Baron, Frederic
    Wouters, Carine
    Liston, Adrian
    JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2016, 138 (01) : 200 - +
  • [3] Dendritic Cell Internalization of α-Galactosylceramide from CD8 T Cells Induces Potent Antitumor CD8 T-cell Responses
    Choi, Dong Hoon
    Kim, Kwang Soon
    Yang, Se Hwan
    Chung, Doo Hyun
    Song, Boyeong
    Sprent, Jonathan
    Cho, Jae Ho
    Sung, Young Chul
    CANCER RESEARCH, 2011, 71 (24) : 7442 - 7451
  • [4] Inhibition of Aurora-A Promotes CD8+ T-Cell Infiltration by Mediating IL10 Production in Cancer Cells
    Han, Jing
    Jiang, Zhen
    Wang, Chennan
    Chen, Xin
    Li, Rongqing
    Sun, Na
    Liu, Xiangye
    Wang, Hui
    Hong, Li
    Zheng, Kuiyang
    Yang, Jing
    Ikezoe, Takayuki
    MOLECULAR CANCER RESEARCH, 2020, 18 (10) : 1589 - 1602
  • [5] Intrinsic β-catenin signaling suppresses CD8 + T-cell infiltration in colorectal cancer (vol 115, 108921, 2019)
    Xue, Junli
    Yu, Xuetao
    Xue, Liqiong
    Ge, Xiaoxiao
    Zhao, Wei
    Peng, Wei
    BIOMEDICINE & PHARMACOTHERAPY, 2020, 132
  • [6] CD8/CD45RO T-cell infiltration in endoscopic biopsies of colorectal cancer predicts nodal metastasis and survival
    Koelzer, Viktor H.
    Lugli, Alessandro
    Dawson, Heather
    Haedrich, Marion
    Berger, Martin D.
    Borner, Markus
    Mallaev, Makhmudbek
    Galvan, Jose A.
    Amsler, Jennifer
    Schnueriger, Beat
    Zlobec, Inti
    Inderbitzin, Daniel
    JOURNAL OF TRANSLATIONAL MEDICINE, 2014, 12
  • [7] CD8/CD45RO T-cell infiltration in endoscopic biopsies of colorectal cancer predicts nodal metastasis and survival
    Viktor H Koelzer
    Alessandro Lugli
    Heather Dawson
    Marion Hädrich
    Martin D Berger
    Markus Borner
    Makhmudbek Mallaev
    José A Galván
    Jennifer Amsler
    Beat Schnüriger
    Inti Zlobec
    Daniel Inderbitzin
    Journal of Translational Medicine, 12
  • [8] Intrinsic β-catenin signaling suppresses CD8+ T-cell infiltration in colorectal cancer
    Xue, Junli
    Yu, Xuetao
    Xue, Liqiong
    Ge, Xiaoxiao
    Zhao, Wei
    Peng, Wei
    BIOMEDICINE & PHARMACOTHERAPY, 2019, 115
  • [9] Metformin Reprograms Tryptophan Metabolism to Stimulate CD8± T-cell Function in Colorectal Cancer
    Huang, Xiaowen
    Sun, Tiantian
    Wang, Jilin
    Hong, Xialu
    Chen, Huimin
    Yan, Tingting
    Zhou, Chengbei
    Sun, Danfeng
    Yang, Chen
    Yu, TaChung
    Su, Wenyu
    Du, Wan
    Xiong, Hua
    CANCER RESEARCH, 2023, 83 (14) : 2358 - 2371
  • [10] Anti-LFA-1 induces CD8 T-cell dependent allograft tolerance and augments suppressor phenotype CD8 cells
    Plenter, Robert J.
    Grazia, Todd J.
    Coulombe, Marilyne G.
    Nelsen, Michelle K.
    Lin, Christine M.
    Beard, K. Scott
    Kupfer, Tinalyn M.
    Zamora, Martin R.
    Gill, Ronald G.
    Pietra, Biagio A.
    CELLULAR IMMUNOLOGY, 2018, 332 : 101 - 110
12345