Gene therapy activates EVI1, destabilizes chromosomes

被引：0
|
作者：
Cynthia E Dunbar
Andre Larochelle
机构：
[1] Cynthia E. Dunbar and Andre Larochelle are in the Hematology Branch,
[2] National Heart,undefined
[3] Lung,undefined
[4] and Blood Institute,undefined
[5] US National Institutes of Health,undefined
[6] Bethesda,undefined
[7] Maryland,undefined
[8] USA.,undefined
来源：
Nature Medicine | 2010年 / 16卷
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学科分类号：
摘要：
One hazard of gene therapy is that the vector will insert into an inappropriate location, causing aberrant expression of genes that can lead to disease. A new study reveals how such events occurred in a recent gene therapy trial using a vector that has now fallen out of favor (pages 198–204).
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页码：163 / 165
页数：2
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