The ATM repair pathway inhibits RNA polymerase I transcription in response to chromosome breaks

被引：0
|
作者：
Michael Kruhlak
Elizabeth E. Crouch
Marika Orlov
Carolina Montaño
Stanislaw A. Gorski
André Nussenzweig
Tom Misteli
Robert D. Phair
Rafael Casellas
机构：
[1] Experimental Immunology,
[2] NCI,undefined
[3] Genomic Integrity and Immunity,undefined
[4] NIAMS,undefined
[5] Biology of Genomes,undefined
[6] NCI,undefined
[7] National Institutes of Health,undefined
[8] Bethesda,undefined
[9] Maryland 20892,undefined
[10] USA,undefined
[11] Integrative Bioinformatics,undefined
[12] Los Altos,undefined
[13] California 94024,undefined
[14] USA,undefined
来源：
Nature | 2007年 / 447卷
关键词：
D O I：
暂无
中图分类号：
学科分类号：
摘要：
DNA damage leads to transient repression of ribosomal gene transcription by RNA polymerase I in a pathway mediated by ATM kinase activity and the DNA repair factors Nbs1 and MDC1
引用
收藏
页码：730 / 734
页数：4
相关论文
共 50 条
  • [41] Nuclear actin and myosin I are required for RNA polymerase I transcription
    Philimonenko, VV
    Zhao, J
    Iben, S
    Dingová, H
    Kyselá, K
    Kahle, M
    Zentgraf, H
    Hofmann, WA
    de Lanerolle, P
    Hozák, P
    Grummt, I
    NATURE CELL BIOLOGY, 2004, 6 (12) : 1165 - 1172
  • [42] Nuclear actin and myosin I are required for RNA polymerase I transcription
    Vlada V. Philimonenko
    Jian Zhao
    Sebastian Iben
    Hana Dingová
    Katarína Kyselá
    Michal Kahle
    Hanswalter Zentgraf
    Wilma A. Hofmann
    Primal de Lanerolle
    Pavel Hozák
    Ingrid Grummt
    Nature Cell Biology, 2004, 6 : 1165 - 1172
  • [43] A regulator that inhibits transcription by targeting an intersubunit interaction of the RNA polymerase holoenzyme
    Gregory, BD
    Nickels, BE
    Garrity, SJ
    Severinova, E
    Minakhin, L
    Urbauer, RJB
    Urbauer, JL
    Heyduk, T
    Severinov, K
    Hochschild, A
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2004, 101 (13) : 4554 - 4559
  • [44] The green tea component EGCG inhibits RNA polymerase III transcription
    Jacob, Joby
    Cabarcas, Stephanie
    Veras, Ingrid
    Zaveri, Nurulain
    Schramm, Laura
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2007, 360 (04) : 778 - 783
  • [45] The yeast transcription terminator for RNA polymerase I is designed to prevent polymerase slippage
    Jeong, SW
    Lang, WH
    Reeder, RH
    JOURNAL OF BIOLOGICAL CHEMISTRY, 1996, 271 (27) : 16104 - 16110
  • [46] DNAPKcs-dependent arrest of RNA polymerase II transcription in the presence of DNA breaks
    Pankotai, Tibor
    Bonhomme, Celine
    Chen, David
    Soutoglou, Evi
    NATURE STRUCTURAL & MOLECULAR BIOLOGY, 2012, 19 (03) : 276 - U29
  • [47] DNAPKcs-dependent arrest of RNA polymerase II transcription in the presence of DNA breaks
    Tibor Pankotai
    Céline Bonhomme
    David Chen
    Evi Soutoglou
    Nature Structural & Molecular Biology, 2012, 19 : 276 - 282
  • [48] NusG inhibits RNA polymerase backtracking by stabilizing the minimal transcription bubble
    Turtola, Matti
    Belogurov, Georgiy A.
    ELIFE, 2016, 5
  • [49] The Transcription Factor THO Promotes Transcription Initiation and Elongation by RNA Polymerase I
    Zhang, Yinfeng
    French, Sarah L.
    Beyer, Ann L.
    Schneider, David A.
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2016, 291 (06) : 3010 - 3018
  • [50] Maf1-mediated repression of RNA polymerase III transcription inhibits tRNA degradation via RTD pathway
    Turowski, Tomasz W.
    Karkusiewicz, Iwona
    Kowal, Justyna
    Boguta, Magdalena
    RNA, 2012, 18 (10) : 1823 - 1832
12345