The ATM repair pathway inhibits RNA polymerase I transcription in response to chromosome breaks

被引：0

作者：

Michael Kruhlak

Elizabeth E. Crouch

Marika Orlov

Carolina Montaño

Stanislaw A. Gorski

André Nussenzweig

Tom Misteli

Robert D. Phair

Rafael Casellas

机构：

[1] Experimental Immunology,

[2] NCI,undefined

[3] Genomic Integrity and Immunity,undefined

[4] NIAMS,undefined

[5] Biology of Genomes,undefined

[6] NCI,undefined

[7] National Institutes of Health,undefined

[8] Bethesda,undefined

[9] Maryland 20892,undefined

[10] USA,undefined

[11] Integrative Bioinformatics,undefined

[12] Los Altos,undefined

[13] California 94024,undefined

[14] USA,undefined

来源：

Nature | 2007年 / 447卷

关键词：

D O I：

暂无

中图分类号：

学科分类号：

摘要：

DNA damage leads to transient repression of ribosomal gene transcription by RNA polymerase I in a pathway mediated by ATM kinase activity and the DNA repair factors Nbs1 and MDC1

引用

页码：730 / 734

页数：4

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