The ATM repair pathway inhibits RNA polymerase I transcription in response to chromosome breaks

被引：0
|
作者：
Michael Kruhlak
Elizabeth E. Crouch
Marika Orlov
Carolina Montaño
Stanislaw A. Gorski
André Nussenzweig
Tom Misteli
Robert D. Phair
Rafael Casellas
机构：
[1] Experimental Immunology,
[2] NCI,undefined
[3] Genomic Integrity and Immunity,undefined
[4] NIAMS,undefined
[5] Biology of Genomes,undefined
[6] NCI,undefined
[7] National Institutes of Health,undefined
[8] Bethesda,undefined
[9] Maryland 20892,undefined
[10] USA,undefined
[11] Integrative Bioinformatics,undefined
[12] Los Altos,undefined
[13] California 94024,undefined
[14] USA,undefined
来源：
Nature | 2007年 / 447卷
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学科分类号：
摘要：
DNA damage leads to transient repression of ribosomal gene transcription by RNA polymerase I in a pathway mediated by ATM kinase activity and the DNA repair factors Nbs1 and MDC1
引用
收藏
页码：730 / 734
页数：4
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