Fatty acid–induced mitochondrial uncoupling elicits inflammasome-independent IL-1α and sterile vascular inflammation in atherosclerosis

被引：0

作者：

Stefan Freigang

Franziska Ampenberger

Adrienne Weiss

Thirumala-Devi Kanneganti

Yoichiro Iwakura

Martin Hersberger

Manfred Kopf

机构：

[1] Institute of Molecular Health Sciences,Division of Clinical Chemistry and Biochemistry

[2] Swiss Federal Institute of Technology (ETH) Zurich,Department of Immunology

[3] University Children's Hospital,undefined

[4] St. Jude Children's Research Hospital,undefined

[5] Research Institute for Biomedical Sciences,undefined

[6] Tokyo University of Science,undefined

来源：

Nature Immunology | 2013年 / 14卷

关键词：

D O I：

暂无

中图分类号：

学科分类号：

摘要：

Chronic inflammation is a fundamental aspect of metabolic disorders such as atherosclerosis. Freigang and colleagues report that fatty acids are potent inducers of IL-1α, which drives vascular inflammation.

引用

页码：1045 / 1053

页数：8

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