Transport of Levofloxacin in the OK Kidney Epithelial Cell Line: Interaction with p-Aminohippurate Transport

被引:0
|
作者
Yumiko Matsuo
Ikuko Yano
Yasushi Habu
Toshiya Katsura
Yukiya Hashimoto
Ken–ichi Inui
机构
[1] Kyoto University,Department of Pharmacy, Kyoto University Hospital, Faculty of Medicine
来源
Pharmaceutical Research | 2001年 / 18卷
关键词
–aminohippurate; quinolone antibacterial drugs; transcellular transport; OK cells; renal secretion; organic anion transport systems;
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摘要
Purpose. To evaluate the mechanism of renal transport of quinolone antibacterial drugs, we examined the interaction of levofloxacin with p–aminohippurate (PAH) transport systems and the transport of levofloxacin in renal epithelial cells.
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页码:573 / 578
页数:5
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