L-proline: a highly effective cryoprotectant for mouse oocyte vitrification

被引：0
|
作者：
Lu Zhang
Xu Xue
Jie Yan
Li-Ying Yan
Xiao-Hu Jin
Xiao-Hui Zhu
Zhi-Zhu He
Jing Liu
Rong Li
Jie Qiao
机构：
[1] Center for Reproductive Medicine,Department of Obstetrics and Gynecology
[2] Peking University Third Hospital,Department of Biomedical Engineering
[3] Beijing Key Laboratory of Reproductive Endocrinology and Assisted Reproduction,undefined
[4] Beijing Key Lab of Cryo-Biomedical Engineering and Key Lab of Cryogenics,undefined
[5] Technical Institute of Physics and Chemistry,undefined
[6] Chinese Academy of Sciences,undefined
[7] Key Laboratory of Assisted Reproduction,undefined
[8] Ministry of Education,undefined
[9] School of Medicine,undefined
[10] Tsinghua University,undefined
来源：
Scientific Reports | / 6卷
关键词：
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Recent studies have shown that L-proline is a natural osmoprotectant and an antioxidant to protect cells from injuries such as that caused by freezing and thawing in many species including plant, ram sperm and human endothelial cells. Nevertheless, this nontoxic cryoprotectant has not yet been applied to mammalian oocyte vitrification. In this study we evaluated the efficiency and safety of the new cryoprotectant in oocyte vitrification. The results indicated that L-proline improves the survival rate of vitrified oocytes, protects mitochondrial functions and could be applied as a new cryoprotectant in mouse oocyte vitrification.
引用
收藏
相关论文
共 50 条
  • [1] L-proline: a highly effective cryoprotectant for mouse oocyte vitrification
    Zhang, Lu
    Xue, Xu
    Yan, Jie
    Yan, Li-Ying
    Jin, Xiao-Hu
    Zhu, Xiao-Hui
    He, Zhi-Zhu
    Liu, Jing
    Li, Rong
    Qiao, Jie
    [J]. SCIENTIFIC REPORTS, 2016, 6
  • [2] Cryobiological Characteristics of L-proline in Mammalian Oocyte Cryopreservation
    Lu Zhang
    Xu Xue
    Jie Yan
    Li-Ying Yan
    Xiao-Hu Jin
    Xiao-Hui Zhu
    Zhi-Zhu He
    Jing Liu
    Rong Li
    Jie Qiao
    [J]. 中华医学杂志(英文版), 2016, 129 (16) : 1963 - 1968
  • [3] Cryobiological Characteristics of L-proline in Mammalian Oocyte Cryopreservation
    Zhang, Lu
    Xue, Xu
    Yan, Jie
    Yan, Li-Ying
    Jin, Xiao-Hu
    Zhu, Xiao-Hui
    He, Zhi-Zhu
    Liu, Jing
    Li, Rong
    Qiao, Jie
    [J]. CHINESE MEDICAL JOURNAL, 2016, 129 (16) : 1963 - 1968
  • [4] L-Proline improves the cytoplasmic maturation of mouse oocyte by regulating glutathione-related redox homeostasis
    Liu, Ning
    Si, Xuemeng
    Ji, Yun
    Yang, Qing
    Bai, Jun
    He, Yu
    Jia, Hai
    Song, Zhuan
    Chen, Jingqing
    Yang, Ling
    Zeng, Shenming
    Yang, Ying
    Wu, Zhenlong
    [J]. THERIOGENOLOGY, 2023, 195 : 159 - 167
  • [5] The effect of poly-L-lysine as a new cryoprotectant for ovine oocyte vitrification.
    Li, N.
    Wuliji, T.
    Qi, A.
    Hyon, S. H.
    Matsumura, K.
    Shi, L.
    Chen, W.
    [J]. JOURNAL OF DAIRY SCIENCE, 2010, 93 : 397 - 397
  • [6] Hydroxypropyl Cellulose as a novel cryoprotectant for oocyte/embryo vitrification
    Mori, C.
    Yabuuchi, A.
    Ezoe, K.
    Takayama, Y.
    Aono, F.
    Kato, K.
    [J]. HUMAN REPRODUCTION, 2013, 28 : 160 - 161
  • [7] L-PROLINE AND L-HISTIDINE IN AUTORADIOGRAM OF SUBCOMMISURAL ORGAN OF MOUSE
    GARWEG, G
    KINSKY, I
    [J]. NATURWISSENSCHAFTEN, 1970, 57 (05) : 253 - &
  • [8] Comparison of two different cryoprotectant formulations for oocyte vitrification.
    Desai, N.
    Julia, S.
    Abdel-Hafez, F.
    Goldfarb, J.
    [J]. FERTILITY AND STERILITY, 2007, 88 : S338 - S338
  • [9] Vitrification of mouse embryos in two cryoprotectant solutions
    Cseh, S
    Horlacher, W
    Brem, G
    Corselli, J
    Seregi, J
    Solti, L
    Bailey, A
    [J]. THERIOGENOLOGY, 1999, 52 (01) : 103 - 113
  • [10] DIFFERENTIAL DISTRIBUTION OF L-HISTIDINE AND L-PROLINE IN AUTORADIOGRAMS OF MOUSE CEREBELLUM
    GARWEG, G
    [J]. NATURWISSENSCHAFTEN, 1969, 56 (09) : 463 - &
12345