A new synthesis of the tripeptide Gly-His-Lys with antimicrobial activity

被引：0
|
作者：
M. Liakopoulou-Kyriakides
C. Pachatouridis
L. Ekateriuiadou
V. P. Papageorgiou
机构：
[1] Aristotle University of Thessaloniki,Department of Chemical Engineering, Section of Chemistry
[2] Aristotle University of Thessaloniki,Faculty of Chemistry
来源：
Amino Acids | 1997年 / 13卷
关键词：
Amino acids; Tripeptide GHK; Synthesis; Antimicrobial activity;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
A new solid phase synthesis of the growth-modulating tripeptide Gly-His-Lys is described. 2-Chlorotrityl chloride resin and 9-fluorenylmethoxycarbonyl-(Fmoc), 4-methyltrityl-(Mtt) protecting groups were used. The synthetic tripeptide was tested for its activity against bacteria, yeast and fungi. The in vitro effect of the tripeptide on DNA, RNA and protein synthesis was studied as well.
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页码：155 / 161
页数：6
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