Metabolite turns master regulator

被引:0
|
作者
Joshua D. Rabinowitz
Thomas J. Silhavy
机构
[1] Princeton University,Joshua D. Rabinowitz is in the Department of Chemistry and at the Lewis
[2] Princeton,Sigler Institute for Integrative Genomics
[3] New Jersey 08544,Thomas J. Silhavy is in the Department of Molecular Biology
[4] USA.,undefined
[5] Princeton University,undefined
[6] Princeton,undefined
[7] New Jersey 08544,undefined
[8] USA.,undefined
来源
Nature | 2013年 / 500卷
关键词
D O I
暂无
中图分类号
学科分类号
摘要
The phenomenon of catabolite repression enables microorganisms to use their favourite carbon source first. New work reveals α-ketoacids as key effectors of this process, with their levels regulating gene expression. See Article p.301
引用
收藏
页码:283 / 284
页数:1
相关论文
共 50 条
  • [41] The lysosome as a master regulator of iron metabolism
    Rizzollo, Francesca
    More, Sanket
    Vangheluwe, Peter
    Agostinis, Patrizia
    TRENDS IN BIOCHEMICAL SCIENCES, 2021, 46 (12) : 960 - 975
  • [42] Oxygen: a master regulator of pancreatic development?
    Fraker, Christopher A.
    Ricordi, Camillo
    Inverardi, Luca
    Dominguez-Bendala, Juan
    BIOLOGY OF THE CELL, 2009, 101 (08) : 431 - 440
  • [43] Should the master regulator Rest in peace?
    Brivanlou, AH
    NATURE GENETICS, 1998, 20 (02) : 109 - 110
  • [44] Mnt - Master regulator of the Max network
    Nilsson, JA
    Cleveland, JL
    CELL CYCLE, 2004, 3 (05) : 588 - 590
  • [45] Nanog is a master regulator of axolotl development
    Dixon, James E.
    Redwood, Catherine
    O'Reilly, Marie-Anne
    Chatfield, Jodie
    Loose, Matt
    Alberio, Ramiro
    Johnson, Andrew D.
    MECHANISMS OF DEVELOPMENT, 2009, 126 : S277 - S277
  • [46] Interferon gamma: A master regulator of atherosclerosis
    McLaren, James E.
    Ramji, Dipak P.
    CYTOKINE & GROWTH FACTOR REVIEWS, 2009, 20 (02) : 125 - 135
  • [47] Identification of a Master Regulator of Differentiation in Toxoplasma
    Waldman, Benjamin S.
    Schwarz, Dominic
    Wadsworth, Marc H., II
    Saeij, Jeroen P.
    Shalek, Alex K.
    Lourido, Sebastian
    CELL, 2020, 180 (02) : 359 - +
  • [48] Changing master regulator without reprogramming
    Lendahl, Urban
    Simon, Andras
    EXPERIMENTAL CELL RESEARCH, 2018, 370 (02) : 189 - 189
  • [49] Proteolysis - A master regulator in health and disease
    Attaix, Didier
    Wing, Simon S.
    INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY, 2016, 79 : 402 - 402
  • [50] Hepcidin: regulation of the master iron regulator
    Rishi, Gautam
    Wallace, Daniel F.
    Subramaniam, V. Nathan
    BIOSCIENCE REPORTS, 2015, 35