Metabolite turns master regulator

被引:0
|
作者
Joshua D. Rabinowitz
Thomas J. Silhavy
机构
[1] Princeton University,Joshua D. Rabinowitz is in the Department of Chemistry and at the Lewis
[2] Princeton,Sigler Institute for Integrative Genomics
[3] New Jersey 08544,Thomas J. Silhavy is in the Department of Molecular Biology
[4] USA.,undefined
[5] Princeton University,undefined
[6] Princeton,undefined
[7] New Jersey 08544,undefined
[8] USA.,undefined
来源
Nature | 2013年 / 500卷
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摘要
The phenomenon of catabolite repression enables microorganisms to use their favourite carbon source first. New work reveals α-ketoacids as key effectors of this process, with their levels regulating gene expression. See Article p.301
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页码:283 / 284
页数:1
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