Synthesis of new daunorubicin N-derivatives by one-step reductive amination

被引:0
|
作者
O. I. Artyushin
E. V. Sharova
N. M. Vinogradova
G. K. Genkina
A. A. Moiseeva
A. A. Khodak
V. K. Brel
机构
[1] Russian Academy of Sciences,Nesmeyanov Institute of Organoelemental Compounds
来源
关键词
anthracycline antibiotics; daunorubicin; reductive amination; aromatic aldehydes; antineoplastic agents;
D O I
暂无
中图分类号
学科分类号
摘要
One-step reductive amination of aromatic aldehydes using an anthracycline antibiotic daunorubicin resulted in the preparation of its new N-derivatives, which are of interest as potential antitumor drugs.
引用
收藏
页码:1323 / 1326
页数:3
相关论文
共 50 条
  • [31] One-step synthesis and pharmacological activity of new (N-substituted)amino-spiroalkan-dione derivatives
    Bonsignore, L
    Loy, G
    Cottiglia, F
    Calignano, A
    FARMACO, 1997, 52 (11): : 663 - 666
  • [32] Reductive amination of ketones: novel one-step transfer hydrogenations in batch and continuous-flow mode
    Falus, Peter
    Boros, Zoltan
    Hornyanszky, Gabor
    Nagy, Jozsef
    Darvas, Ferenc
    Uerge, Laszlo
    Poppe, Laszlo
    TETRAHEDRON LETTERS, 2011, 52 (12) : 1310 - 1312
  • [33] One-step synthesis of N-acetylcysteine and glutathione derivatives using the Ugi reaction
    Zhdanko, Alexander G.
    Gulevich, Anton V.
    Nenajdenko, Valentine G.
    TETRAHEDRON, 2009, 65 (24) : 4692 - 4702
  • [34] A One-Step Preparation of Tetradentate Ligands with Nitrogen and Phosphorus Donors by Reductive Amination and Representative Iron Complexes
    Gradiski, Matthew, V
    Kharat, Ali Nemati
    Ong, Maegan S. E.
    Lough, Alan J.
    Smith, Samantha A. M.
    Morris, Robert H.
    INORGANIC CHEMISTRY, 2020, 59 (15) : 11041 - 11053
  • [35] Preparative method of synthesis of 2-thioxothiazolidin-4-one N-derivatives
    Orlinskii, MM
    ZHURNAL ORGANICHESKOI KHIMII, 1996, 32 (01): : 144 - 145
  • [36] One-step synthesis of a new heterocyclophane family
    Quevedo, Rodolfo
    Moreno-Murillo, Barbara
    TETRAHEDRON LETTERS, 2009, 50 (08) : 936 - 938
  • [37] A new one-step synthesis of functionalized fulvenes
    Himeda, Y
    Ueda, I
    Hatanaka, M
    CHEMISTRY LETTERS, 1996, (01) : 71 - 72
  • [38] One-step synthesis of new heterocyclic azacyanines
    Haddadin, MJ
    Kurth, JM
    Olmstead, MM
    TETRAHEDRON LETTERS, 2000, 41 (30) : 5613 - 5616
  • [39] A new one-step method for oxaadamantane synthesis
    Krasutsky, PA
    Kolomitsin, IV
    Carlson, RM
    Jones, M
    TETRAHEDRON LETTERS, 1996, 37 (32) : 5673 - 5674
  • [40] NEW ONE-STEP SYNTHESIS OF HEXAHYDROCANNABINOID ANALOGS
    DIKE, SY
    KAMATH, M
    MERCHANT, JR
    EXPERIENTIA, 1977, 33 (08): : 985 - 985