The HTLV-1 Tax interactome

被引：0
|
作者：
Mathieu Boxus
Jean-Claude Twizere
Sébastien Legros
Jean-François Dewulf
Richard Kettmann
Luc Willems
机构：
[1] University Academia Wallonie-Europe,Molecular and Cellular Biology at FUSAGx
来源：
Retrovirology | / 5卷
关键词：
Bovine Leukemia Virus; Spindle Assembly Checkpoint; Centrosome Amplification; Basal Transcription Factor; Mitotic Spindle Assembly Checkpoint;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
The Tax1 oncoprotein encoded by Human T-lymphotropic virus type I is a major determinant of viral persistence and pathogenesis. Tax1 affects a wide variety of cellular signalling pathways leading to transcriptional activation, proliferation and ultimately transformation. To carry out these functions, Tax1 interacts with and modulates activity of a number of cellular proteins. In this review, we summarize the present knowledge of the Tax1 interactome and propose a rationale for the broad range of cellular proteins identified so far.
引用
下载
收藏
相关论文
共 50 条
  • [41] Effects of Tax vaccine adjuvants in HTLV-1 humanized mice
    Tanaka, Masakazu
    Fukuhara, Takataro
    Lee, Sung-il
    Ren, Yihua
    Yao, Jinchun
    Takenouchi, Norihiro
    Ueda, Yoshihiro
    Kinashi, Tatsuo
    Fujisawa, Jun-ichi
    CANCER SCIENCE, 2018, 109 : 196 - 196
  • [42] Transformation of human embryonic stem cells by HTLV-1 Tax
    Linda Zane
    Junichiro Yasunaga
    Takao Kinjo
    Gustavo Brito de Melo
    Kuan-Teh Jeang
    Retrovirology, 8 (Suppl 1)
  • [43] Regulation of NF-κB by the HTLV-1 Tax protein
    Li, XH
    Gaynor, RB
    GENE EXPRESSION, 1999, 7 (4-6): : 233 - 245
  • [44] Role of HTLV-1 Tax and HBZ in the Pathogenesis of HAM/TSP
    Enose-Akahata, Yoshimi
    Vellucci, Ashley
    Jacobson, Steven
    FRONTIERS IN MICROBIOLOGY, 2017, 8
  • [45] CELLULAR-TRANSFORMATION AND APOPTOSIS BY TAX GENE OF HTLV-1
    HATANAKA, M
    JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES AND HUMAN RETROVIROLOGY, 1995, 10 (02): : 27 - 27
  • [46] HTLV-1 Tax and adult T-cell leukemia
    Giam, Chou-Zen
    Jeang, Kuan-Teh
    FRONTIERS IN BIOSCIENCE, 2007, 12 : 1496 - 1507
  • [47] CBP: A target molecule of HTLV-1 Tax in synoviocyte activation
    Nakazawa, M
    Hasunuma, T
    Ohshima, T
    Tanaka, Y
    Nishioka, K
    Nakajima, T
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2000, 269 (02) : 584 - 590
  • [48] Interaction of HTLV-1 Tax with the proteins of cellular secretory pathway
    Flaig, K
    Jain, P
    Wigdahl, B
    AIDS RESEARCH AND HUMAN RETROVIRUSES, 2005, 21 (05) : 511 - 511
  • [49] HTLV-1
    SORIANO, V
    GUTIERREZ, M
    TUSET, C
    CALDERON, E
    REVISTA CLINICA ESPANOLA, 1994, 194 (07): : 551 - 557
  • [50] VERTICAL TRANSMISSION OF HTLV-1 IN HTLV-1 CARRIER RAT
    AMI, Y
    KUSHIDA, S
    MATSUMURA, M
    YOSHIDA, Y
    KAMEYAMA, T
    SUGIYAMA, Y
    YAGAMI, K
    UCHIDA, M
    UCHIDA, K
    KOISO, K
    MIWA, M
    JAPANESE JOURNAL OF CANCER RESEARCH, 1992, 83 (12): : 1241 - 1243
12345