The HTLV-1 Tax interactome

被引：0
|
作者：
Mathieu Boxus
Jean-Claude Twizere
Sébastien Legros
Jean-François Dewulf
Richard Kettmann
Luc Willems
机构：
[1] University Academia Wallonie-Europe,Molecular and Cellular Biology at FUSAGx
来源：
Retrovirology | / 5卷
关键词：
Bovine Leukemia Virus; Spindle Assembly Checkpoint; Centrosome Amplification; Basal Transcription Factor; Mitotic Spindle Assembly Checkpoint;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
The Tax1 oncoprotein encoded by Human T-lymphotropic virus type I is a major determinant of viral persistence and pathogenesis. Tax1 affects a wide variety of cellular signalling pathways leading to transcriptional activation, proliferation and ultimately transformation. To carry out these functions, Tax1 interacts with and modulates activity of a number of cellular proteins. In this review, we summarize the present knowledge of the Tax1 interactome and propose a rationale for the broad range of cellular proteins identified so far.
引用
下载
收藏
相关论文
共 50 条
  • [1] The HTLV-1 Tax interactome
    Boxus, Mathieu
    Twizere, Jean-Claude
    Legros, Sebastien
    Dewulf, Jean-Francois
    Kettmann, Richard
    Willems, Luc
    RETROVIROLOGY, 2008, 5 (1)
  • [2] Mechanisms of action of HTLV-1 Tax
    Yao, Y
    Kuo, YL
    Wang, LC
    Harrod, R
    Tang, Y
    Cai, P
    Harrington, WJ
    Boros, I
    Shih, HM
    Giam, CZ
    LEUKEMIA, 2000, 14 (03) : 535 - 535
  • [3] Mechanisms of Oncogenesis by HTLV-1 Tax
    Mohanty, Suchitra
    Harhaj, Edward W.
    PATHOGENS, 2020, 9 (07): : 1 - 28
  • [4] SUV39H1 interacts with HTLV-1 Tax and abrogates Tax transactivation of HTLV-1 LTR
    Kamoi, K
    Misawa, A
    Yamamoto, K
    Ishida, T
    Mochizuki, M
    Watanabe, T
    AIDS RESEARCH AND HUMAN RETROVIRUSES, 2005, 21 (05) : 500 - 500
  • [5] SUV39H1 interacts with HTLV-1 Tax and abrogates Tax transactivation of HTLV-1 LTR
    Koju Kamoi
    Keiyu Yamamoto
    Aya Misawa
    Ariko Miyake
    Takaomi Ishida
    Yuetsu Tanaka
    Manabu Mochizuki
    Toshiki Watanabe
    Retrovirology, 3
  • [6] Transformation of Human Cells by HTLV-1 Tax
    Jeang, Kuan-Teh
    JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES, 2012, 59 : 65 - 65
  • [7] HTLV-1 Tax protein triggers microtubule
    Nejmeddine, M
    Barnard, AL
    Taylor, GP
    Tanaka, Y
    Bangham, CR
    AIDS RESEARCH AND HUMAN RETROVIRUSES, 2005, 21 (05) : 509 - 510
  • [8] NEW TARGETS OF TAX PROTEIN OF HTLV-1
    YOSHIDA, M
    SAITO, M
    TANIMURA, A
    SUZUKI, T
    AIDS RESEARCH AND HUMAN RETROVIRUSES, 1995, 11 : S124 - S124
  • [9] The role of Htlv-1 Tax in chromatin remodeling
    Deng, L
    Kehn, K
    De La Fuente, C
    Pumfery, A
    Kashanchi, F
    AIDS RESEARCH AND HUMAN RETROVIRUSES, 2005, 21 (05) : 450 - 450
  • [10] HTLV-1 Tax: centrosome amplification and cancer
    Anne Pumfery
    Cynthia de la Fuente
    Fatah Kashanchi
    Retrovirology, 3
12345