A phase I safety, pharmacological, and biological study of the farnesyl protein transferase inhibitor, lonafarnib (SCH 663366), in combination with cisplatin and gemcitabine in patients with advanced solid tumors

被引:0
|
作者
Laura Q. M. Chow
S. Gail Eckhardt
Cindy L. O’Bryant
Mary Kay Schultz
Mark Morrow
Stacy Grolnic
Michele Basche
Lia Gore
机构
[1] University of Colorado Cancer Center,
[2] The Children’s Hospital,undefined
[3] University of Colorado Health Sciences Center at Fitzsimons,undefined
来源
Cancer Chemotherapy and Pharmacology | 2008年 / 62卷
关键词
Lonafarnib; SCH66336; Cisplatin; Gemcitabine; Farnesyltransferase; Phase I; Pharmacokinetics;
D O I
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中图分类号
学科分类号
摘要
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页码:631 / 646
页数:15
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