Effects of the histamine H1 receptor antagonist hydroxyzine on hERG K+ channels and cardiac action potential duration

被引:0
|
作者
Byung Hoon Lee
Seung Ho Lee
Daehyun Chu
Jin Won Hyun
Han Choe
Bok Hee Choi
Su-Hyun Jo
机构
[1] Institute of Bioscience and Biotechnology,Department of Physiology
[2] Kangwon National University School of Medicine,Department of Radiology
[3] Ilsan Paik Hospital,Department of Pharmacology
[4] Inje University School of Medicine,Department of Physiology
[5] Institute for Medical Sciences,Department of Biochemistry
[6] Chonbuk National University Medical School,undefined
[7] Bio-Medical Institute of Technology,undefined
[8] University of Ulsan College of Medicine,undefined
[9] School of Medicine,undefined
[10] Jeju National University,undefined
来源
关键词
histamine antagonists; hydroxyzine; cardiomyocytes; hERG channels; K; channel; proarrhythmic effects;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
页码:1128 / 1137
页数:9
相关论文
共 50 条
  • [31] In vitro characterisation of the duration of action of the histamine-1 receptor antagonist azelastine
    Slack, Robert J.
    Hart, Adam D.
    Luttmann, Mark A.
    Clark, Kenneth L.
    Begg, Malcolm
    EUROPEAN JOURNAL OF PHARMACOLOGY, 2011, 670 (2-3) : 586 - 592
  • [32] Effects of the histamine H1 receptor antagonist and benztropine analog diphenylpyraline on dopamine uptake, locomotion and reward
    Oleson, Erik B.
    Ferris, Mark J.
    Espana, Rodrigo A.
    Harp, Jill
    Jones, Sara R.
    EUROPEAN JOURNAL OF PHARMACOLOGY, 2012, 683 (1-3) : 161 - 165
  • [33] Effects of vasopressin on histamine H1 receptor antagonist-induced spatial memory deficits in rats
    Taga, C
    Sugimoto, Y
    Nishiga, M
    Fujii, Y
    Kamei, C
    EUROPEAN JOURNAL OF PHARMACOLOGY, 2001, 423 (2-3) : 167 - 170
  • [34] Design and synthesis of novel dual histamine H1/H3 receptor antagonists based on the H1 receptor antagonist chlorpheniramine.
    Aslanian, R
    Mutahi, MW
    Tom, W
    Shih, NY
    Piwinski, JJ
    West, R
    Williams, SM
    She, S
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2002, 223 : A98 - A98
  • [35] Effects of the Histamine H1 Antagonist Chlorcyclizine on Rat Fetal Palate Development
    Enright, Brian P.
    Gu, Yi-Zhong
    Snyder, Ronald D.
    Dugyala, Ravi R.
    Obert, Leslie A.
    Treinen, Kimberley A.
    McIntyre, Barry S.
    Veneziale, Robert W.
    BIRTH DEFECTS RESEARCH PART B-DEVELOPMENTAL AND REPRODUCTIVE TOXICOLOGY, 2010, 89 (06) : 474 - 484
  • [36] CARDIAC ELECTROPHYSIOLOGICAL EFFECTS OF HISTAMINE, H1 AND H2 AGONISTS
    KECSKEMETI, V
    AGENTS AND ACTIONS, 1993, 38 : C292 - C294
  • [37] ROLE OF LARGE CONDUCTANCE CA2+ ACTIVATED K+ CHANNELS IN THE ACTIONS OF A HISTAMINE H1 RECEPTOR AGONIST IN RABBIT CORONARY-ARTERIES
    ISHIKAWA, T
    ECKMAN, DM
    HUME, JR
    KEEF, KD
    FASEB JOURNAL, 1992, 6 (01): : A255 - A255
  • [38] BILASTINE Histamine H1 Receptor Antagonist Treatment of Allergic Rhinitis Treatment of Urticaria
    Ferrer, E.
    Pandian, R.
    Bolos, J.
    Castaner, R.
    DRUGS OF THE FUTURE, 2010, 35 (02) : 98 - 105
  • [39] Effect of Ions and Sequence Variants on the Antagonist Binding Properties of the Histamine H1 Receptor
    Conrad, Marcus
    Soeldner, Christian A.
    Sticht, Heinrich
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2022, 23 (03)
  • [40] In vivo pharmacological characterisation of bilastine, a potent and selective histamine H1 receptor antagonist
    Corcóstegui R.
    Labeaga L.
    Innerárity A.
    Berisa A.
    Orjales A.
    Drugs in R & D, 2006, 7 (4) : 219 - 231