Microdialysis Studies of the Distribution of Stavudine into the Central Nervous System in the Freely-Moving Rat

被引：0
|
作者：
Zheng Yang
Richard C. Brundage
Rashmi H. Barbhaiya
Ronald J. Sawchuk
机构：
[1] University of Minnesota,Graduate Program in Pharmaceutics, College of Pharmacy
[2] Bristol-Myers Squibb Co.,Pharmaceutical Research Institute, Dept. of Pharmacokinetics and Drug Metabolism
来源：
Pharmaceutical Research | 1997年 / 14卷
关键词：
stavudine; zidovudine; microdialysis; retrodialysis; central nervous system; brain uptake; blood-brain barrier; intracerebroventricular administration; AIDS;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Purpose. To study the extent and time course of distribution of stavudine (d4T) into the central nervous system (CNS) and to investigate the transport mechanisms of antiviral nucleosides in the CNS.
引用
收藏
页码：865 / 872
页数：7
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