Microdialysis Studies of the Distribution of Stavudine into the Central Nervous System in the Freely-Moving Rat

被引：0
|
作者：
Zheng Yang
Richard C. Brundage
Rashmi H. Barbhaiya
Ronald J. Sawchuk
机构：
[1] University of Minnesota,Graduate Program in Pharmaceutics, College of Pharmacy
[2] Bristol-Myers Squibb Co.,Pharmaceutical Research Institute, Dept. of Pharmacokinetics and Drug Metabolism
来源：
Pharmaceutical Research | 1997年 / 14卷
关键词：
stavudine; zidovudine; microdialysis; retrodialysis; central nervous system; brain uptake; blood-brain barrier; intracerebroventricular administration; AIDS;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Purpose. To study the extent and time course of distribution of stavudine (d4T) into the central nervous system (CNS) and to investigate the transport mechanisms of antiviral nucleosides in the CNS.
引用
下载
收藏
页码：865 / 872
页数：7
相关论文
共 50 条
  • [11] AN ELECTRO-MYOGRAPHIC STUDY OF MASTICATION IN THE FREELY-MOVING RAT
    THOMAS, NR
    PEYTON, SC
    ARCHIVES OF ORAL BIOLOGY, 1983, 28 (10) : 939 - 945
  • [12] DEPLETION OF CENTRAL BETA-ENDORPHIN BLOCKS MIDBRAIN STIMULATION PRODUCED ANALGESIA IN THE FREELY-MOVING RAT
    MILLAN, MH
    MILLAN, MJ
    HERZ, A
    NEUROSCIENCE, 1986, 18 (03) : 641 - 649
  • [13] Striatal dopamine measurement in the freely-moving rat using wireless voltammetry
    Kagohashi, M.
    Moizumi, S.
    Yoshimi, K.
    Nakazato, T.
    Kitazawa, S.
    Mizuno, Y.
    MOVEMENT DISORDERS, 2006, 21 : S351 - S351
  • [14] EFFECTS OF MORPHINE ON CHOLINERGIC SYSTEM IN THE STRIATUM OF FREELY MOVING RATS - INVIVO MICRODIALYSIS STUDIES
    TAGUCHI, K
    SUZUKI, Y
    EUROPEAN JOURNAL OF PHARMACOLOGY, 1990, 183 (05) : 1933 - 1933
  • [15] Peritoneal microdialysis in freely moving rodents: An alternative to blood sampling for pharmacokinetic studies in the rat and the mouse
    Beier, Horst
    Kaiser, Katharina
    Langhans, Manfred
    Malmendier, Klaus
    Sluijsmans, Ivo
    Weiher, Juergen
    EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2007, 30 (01) : 75 - 83
  • [16] The evoked release of GABA and taurine from the striato-pallidal (indirect) pathway: A dual probe microdialysis study in the freely-moving rat
    Fattori, M
    Bianchi, L
    Colivicchi, MA
    Chechi, M
    Bolam, JP
    Della Corte, L
    BRITISH JOURNAL OF PHARMACOLOGY, 2001, 133 : U90 - U90
  • [17] 4π measurement system: A complete volume reconstruction system for freely-moving objects
    IEEE Industrial Electronics Society; IEEE Robotics and Automation Society; Robotics Society of Japan; Society of Instrument and Control Engineers of Japan (Institute of Electrical and Electronics Engineers Inc., United States):
  • [18] EFFECTS OF THE BENZODIAZEPINE PARTIAL INVERSE AGONIST, RU-33965, ON HIPPOCAMPAL ACETYLCHOLINE-RELEASE IN THE FREELY-MOVING RAT - A MICRODIALYSIS STUDY
    KULKARNI, RS
    BENNETT, GW
    MARSDEN, CA
    GARDNER, CR
    BRITISH JOURNAL OF PHARMACOLOGY, 1994, 111 : P143 - P143
  • [19] 4π measurement system:: A complete volume reconstruction system for freely-moving objects
    Iiyama, M
    Kameda, Y
    Minoh, M
    PROCEEDINGS OF THE IEEE INTERNATIONAL CONFERENCE ON MULTISENSOR FUSION AND INTEGRATION FOR INTELLIGENT SYSTEMS, 2003, : 119 - 124
  • [20] Helium-oxygen pressure induces striatal glutamate increase: a microdialysis study in freely-moving rats
    Darbin, O
    Risso, JJ
    Rostain, JC
    NEUROSCIENCE LETTERS, 2001, 297 (01) : 37 - 40
12345