Microdialysis Studies of the Distribution of Stavudine into the Central Nervous System in the Freely-Moving Rat

被引：0
|
作者：
Zheng Yang
Richard C. Brundage
Rashmi H. Barbhaiya
Ronald J. Sawchuk
机构：
[1] University of Minnesota,Graduate Program in Pharmaceutics, College of Pharmacy
[2] Bristol-Myers Squibb Co.,Pharmaceutical Research Institute, Dept. of Pharmacokinetics and Drug Metabolism
来源：
Pharmaceutical Research | 1997年 / 14卷
关键词：
stavudine; zidovudine; microdialysis; retrodialysis; central nervous system; brain uptake; blood-brain barrier; intracerebroventricular administration; AIDS;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Purpose. To study the extent and time course of distribution of stavudine (d4T) into the central nervous system (CNS) and to investigate the transport mechanisms of antiviral nucleosides in the CNS.
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页码：865 / 872
页数：7
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