The implication of dihydrofolate reductase and dihydropteroate synthetase gene mutations in modification of Plasmodium falciparum characteristics

被引:0
|
作者
Ishraga E A-Elbasit
Michael Alifrangis
Insaf F Khalil
Ib C Bygbjerg
Emad M Masuadi
Mustafa I Elbashir
Hayder A Giha
机构
[1] University of Khartoum,Malaria Research Centre (MalRC), Department of Biochemistry, Faculty of Medicine
[2] University of Copenhagen,Centre for Medical Parasitology (CMP) at Institute of Medical Microbiology and Immunology and Institute of Public Health
[3] Arabian Gulf University (AGU),Department of Biochemistry, and Department of Family & Community Medicine, Faculty of Medicine and Medical Sciences
来源
关键词
Malaria; Parasite Infection; Single Nucleotide Polymorphism; Falciparum Malaria; Parasite Density;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
相关论文
共 50 条
  • [31] Polymorphisms in Plasmodium falciparum dihydropteroate synthetase and dihydrofolate reductase genes in Nigerian children with uncomplicated malaria using high-resolution melting technique
    Adeyemi T. Kayode
    Fehintola V. Ajogbasile
    Kazeem Akano
    Jessica N. Uwanibe
    Paul E. Oluniyi
    Philomena J. Eromon
    Onikepe A. Folarin
    Akintunde Sowunmi
    Dyann F. Wirth
    Christian T. Happi
    Scientific Reports, 11
  • [32] Polymorphisms in Plasmodium falciparum dihydropteroate synthetase and dihydrofolate reductase genes in Nigerian children with uncomplicated malaria using high-resolution melting technique
    Kayode, Adeyemi T.
    Ajogbasile, Fehintola V.
    Akano, Kazeem
    Uwanibe, Jessica N.
    Oluniyi, Paul E.
    Eromon, Philomena J.
    Folarin, Onikepe A.
    Sowunmi, Akintunde
    Wirth, Dyann F.
    Happi, Christian T.
    SCIENTIFIC REPORTS, 2021, 11 (01)
  • [33] Polymorphism in drug resistance genes dihydrofolate reductase and dihydropteroate synthase in Plasmodium falciparum in some states of India
    Sharma, Divya
    Lather, Manila
    Mallick, Prashant K.
    Adak, Tridibes
    Dang, Amita S.
    Valecha, Neena
    Singh, Om P.
    PARASITES & VECTORS, 2015, 8
  • [34] Polymorphism in drug resistance genes dihydrofolate reductase and dihydropteroate synthase in Plasmodium falciparum in some states of India
    Divya Sharma
    Manila Lather
    Prashant K. Mallick
    Tridibes Adak
    Amita S. Dang
    Neena Valecha
    Om P. Singh
    Parasites & Vectors, 8
  • [35] Mutational analysis of Plasmodium falciparum dihydrofolate reductase and dihydropteroate synthase genes in the interior division of Sabah, Malaysia
    Lau, Tiek Ying
    Sylvi, Mersumpin
    William, Timothy
    MALARIA JOURNAL, 2013, 12
  • [36] Pyrosequencing-A high-throughput method for detecting single nucleotide polymorphisms (SNPS) in the dihydrofolate reductase and dihydropteroate synthetase genes of Plasmodium falciparum
    Zhou, Zhiyong
    Poe, Amanda
    Limor, Josef
    Grady, Katharine K.
    Goldman, Ira
    McCollum, Andrea
    Escalante, Ananias
    Barnwell, John W.
    Udhayakumar, Venkatachalam
    AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE, 2006, 75 (05): : 56 - 56
  • [37] Resistance to antifolates in Plasmodium falciparum monitored by sequence analysis of dihydropteroate synthetase and dihydrofolate reductase alleles in a large number of field samples of diverse origins
    Wang, P
    Lee, CS
    Bayoumi, R
    Djimde, A
    Doumbo, O
    Swedberg, G
    Dao, LD
    Mshinda, H
    Tanner, M
    Watkins, WM
    Sims, PFG
    Hyde, JE
    MOLECULAR AND BIOCHEMICAL PARASITOLOGY, 1997, 89 (02) : 161 - 177
  • [38] Mutational analysis of Plasmodium falciparum dihydrofolate reductase and dihydropteroate synthase genes in the interior division of Sabah, Malaysia
    Tiek Ying Lau
    Mersumpin Sylvi
    Timothy William
    Malaria Journal, 12
  • [39] Genetic mutations in Plasmodium falciparum and Plasmodium vivax dihydrofolate reductase (DHFR) and dihydropteroate synthase (DHPS) in Vanuatu and Solomon Islands prior to the introduction of artemisinin combination therapy
    Gresty, Karryn J.
    Gray, Karen-Ann
    Bobogare, Albino
    Wini, Lyndes
    Taleo, George
    Hii, Jeffrey
    Cheng, Qin
    Waters, Norman C.
    MALARIA JOURNAL, 2014, 13
  • [40] Plasmodium falciparum:: Gene mutations and amplification of dihydrofolate reductase genes in parasites grown in vitro in presence of pyrimethamine
    Thaithong, S
    Ranford-Cartwright, LC
    Siripoon, N
    Harnyuttanakorn, P
    Kanchanakhan, NS
    Seugorn, A
    Rungsihirunrat, K
    Cravo, PVL
    Beale, GH
    EXPERIMENTAL PARASITOLOGY, 2001, 98 (02) : 59 - 70