Analysis of the γ-secretase interactome and validation of its association with tetraspanin-enriched microdomains

被引：0

作者：

Tomoko Wakabayashi

Katleen Craessaerts

Leen Bammens

Mostafa Bentahir

Filip Borgions

Piet Herdewijn

An Staes

Evy Timmerman

Joël Vandekerckhove

Eric Rubinstein

Claude Boucheix

Kris Gevaert

Bart De Strooper

机构：

[1] Center for Human Genetics,Department for molecular and developmental genetics

[2] K.U.Leuven,Department of Biochemistry

[3] VIB,undefined

[4] Flanders Institute for Biotechnology,undefined

[5] Laboratory of Medicinal Chemistry,undefined

[6] K.U.Leuven,undefined

[7] Department of Medical Protein Research,undefined

[8] Ghent University,undefined

[9] Inserm,undefined

[10] U602,undefined

[11] Université Paris 11,undefined

[12] Institut André Lwoff,undefined

来源：

Nature Cell Biology | 2009年 / 11卷

关键词：

D O I：

暂无

中图分类号：

学科分类号：

摘要：

The γ-secretase complex is responsible for the generation of amyloid β-peptide, the main component of Alzheimer's disease associated plaques. A proteomic analysis yielded secretory pathway components and membrane-associated tetraspannin microdomains as interactors and regulators of the γ-secretase complex.

引用

页码：1340 / 1346

页数：6

共 37 条

[1] Analysis of the γ-secretase interactome and validation of its association with tetraspanin-enriched microdomains
Wakabayashi, Tomoko
Craessaerts, Katleen
Bammens, Leen
Bentahir, Mostafa
Borgions, Filip
Herdewijn, Piet
Staes, An
Timmerman, Evy
Vandekerckhove, Joel
Rubinstein, Eric
Boucheix, Claude
Gevaert, Kris
De Strooper, Bart
NATURE CELL BIOLOGY, 2009, 11 (11) : 1340 - U181
[2] Tetraspanin-enriched microdomains regulate digitation junctions
Chao Huang
Chenying Fu
Jonathan D. Wren
Xuejun Wang
Feng Zhang
Yanhui H. Zhang
Samuel A. Connel
Taosheng Chen
Xin A. Zhang
Cellular and Molecular Life Sciences, 2018, 75 : 3423 - 3439
[3] The Intracellular Interactome of Tetraspanin-enriched Microdomains Reveals Their Function as Sorting Machineries toward Exosomes
Perez-Hernandez, Daniel
Gutierrez-Vazquez, Cristina
Jorge, Inmaculada
Lopez-Martin, Soraya
Ursa, Angeles
Sanchez-Madrid, Francisco
Vazquez, Jesus
Yanez-Mo, Maria
JOURNAL OF BIOLOGICAL CHEMISTRY, 2013, 288 (17) : 11649 - 11661
[4] Tetraspanin-enriched microdomains regulate digitation junctions
Huang, Chao
Fu, Chenying
Wren, Jonathan D.
Wang, Xuejun
Zhang, Feng
Zhang, Yanhui H.
Connel, Samuel A.
Chen, Taosheng
Zhang, Xin A.
CELLULAR AND MOLECULAR LIFE SCIENCES, 2018, 75 (18) : 3423 - 3439
[5] Tetraspanin-enriched microdomains and hepatocellular carcinoma progression
Mazzocca, Antonio
Birgani, Maryam Tahmasebi
Sabba, Carlo
Carloni, Vinicio
CANCER LETTERS, 2014, 351 (01) : 23 - 29
[6] Tetraspanin 8 is an interactor of the metalloprotease meprin β within tetraspanin-enriched microdomains
Schmidt, Frederike
Mueller, Miryam
Prox, Johannes
Arnold, Philipp
Schoenherr, Caroline
Tredup, Claudia
Minder, Petra
Ebsen, Henriette
Janssen, Ottmar
Annaert, Wim
Pietrzik, Claus
Schmidt-Arras, Dirk
Sterchi, Erwin E.
Becker-Pauly, Christoph
BIOLOGICAL CHEMISTRY, 2016, 397 (09) : 857 - 869
[7] Correction to: Tetraspanin-enriched microdomains regulate digitation junctions
Chao Huang
Chenying Fu
Jonathan D. Wren
Xuejun Wang
Feng Zhang
Yanhui H. Zhang
Samuel A. Connell
Taosheng Chen
Xin A. Zhang
Cellular and Molecular Life Sciences, 2018, 75 : 4077 - 4077
[8] Tetraspanin-enriched microdomains: a functional unit in cell plasma membranes
Yanez-Mo, Maria
Barreiro, Olga
Gordon-Alonso, Monica
Sala-Valdes, Monica
Sanchez-Madrid, Francisco
TRENDS IN CELL BIOLOGY, 2009, 19 (09) : 434 - 446
[9] Implicaton of tetraspanin-enriched microdomains (TEMs) in hepatitis C virus
Sanz-Cameno, Paloma
Martin-Vilchez, Samuel
Rodriguez-Munoz, Yolanda
Moreno-Otero, Ricardo
HEPATOLOGY, 2008, 48 (01) : 346 - 348
[10] Gangliosides play a critical role in the organization of the tetraspanin-enriched microdomains
Odintsova, E
Butters, TD
Schnaar, RL
Berditchevski, F
FEBS JOURNAL, 2005, 272 : 225 - 225

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