Role of the promyelocytic leukaemia protein in cell death regulation

被引：0
|
作者：
P Salomoni
M Dvorkina
D Michod
机构：
[1] Samantha Dickson Brain Cancer Unit,
[2] UCL Cancer Institute,undefined
来源：
Cell Death & Disease | 2012年 / 3卷
关键词：
Snail; HNF4; miRs-200; miR-34a; stemness;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
The promyelocytic leukaemia gene PML was originally identified at the t(15;17) translocation of acute promyelocytic leukaemia, which generates the oncogene PML-retinoic acid receptor α. PML epitomises a subnuclear structure called PML nuclear body. Current models propose that PML through its scaffold properties is able to control cell growth and survival at many different levels. Here we discuss the current literature and propose new avenues for investigation.
引用
收藏
页码：e247 / e247
相关论文
共 50 条
  • [21] Analysis of early death in critically ill patients with acute promyelocytic leukaemia in the HICU
    Li, Haitao
    Zhang, Yingmei
    Fan, Shengjin
    Li, Dandan
    Zhang, Qian
    Fu, Jinyue
    Lu, Dongxue
    Ji, Jiajuan
    Li, Yinghua
    SCIENTIFIC REPORTS, 2024, 14 (01):
  • [22] Expression of cell-surface antigens in acute promyelocytic leukaemia
    Paietta, E
    BEST PRACTICE & RESEARCH CLINICAL HAEMATOLOGY, 2003, 16 (03) : 369 - 385
  • [23] Stem cell transplantation in acute promyelocytic leukaemia: the Iranian experience
    Ghavamzadeh, A.
    Alimoghaddam, K.
    Jahani, M.
    Mousavi, A.
    Bahar, B.
    Iravani, M.
    Jorjani, H.
    Jalali, A.
    Derakhshandeh, R.
    BONE MARROW TRANSPLANTATION, 2011, 46 : S286 - S287
  • [24] Death associated protein 1 is correlated with the clinical outcome of patients with colorectal cancer and has a role in the regulation of cell death
    Jia, Yongning
    Ye, Lin
    Ji, Ke
    Toms, Ann-Marie
    Davies, Mansel Leigh
    Ruge, Fiona
    Ji, Jiafu
    Hargest, Rachel
    Jiang, Wen G.
    ONCOLOGY REPORTS, 2014, 31 (01) : 175 - 182
  • [25] Role of the unfolded protein response in cell death
    R. Kim
    M. Emi
    K. Tanabe
    S. Murakami
    Apoptosis, 2006, 11 : 5 - 13
  • [26] Role of the unfolded protein response in cell death
    Kim, R
    Emi, M
    Tanabe, K
    Murakami, S
    APOPTOSIS, 2006, 11 (01) : 5 - 13
  • [27] The role of cell death regulation in cancer prevention.
    Thompson, CB
    CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION, 2005, 14 (11) : 2771S - 2771S
  • [28] Metabolic regulation of the PMCA: Role in cell death and survival
    Bruce, Jason I. E.
    CELL CALCIUM, 2018, 69 : 28 - 36
  • [29] Uncovering the role of VDAC in the regulation of cell life and death
    Shoshan-Barmatz, Varda
    Keinan, Nurit
    Zaid, Hilal
    JOURNAL OF BIOENERGETICS AND BIOMEMBRANES, 2008, 40 (03) : 183 - 191
  • [30] Uncovering the role of VDAC in the regulation of cell life and death
    Varda Shoshan-Barmatz
    Nurit Keinan
    Hilal Zaid
    Journal of Bioenergetics and Biomembranes, 2008, 40 : 183 - 191
12345