Putative role of epithelial sodium channels (ENaC)in the afferent limb of cardio renal reflexes in rats

被引：0
|
作者：
Tilmann Ditting
Peter Linz
Karl F. Hilgers
Oliver Jung
Helmut Geiger
Roland Veelken
机构：
[1] J. W. Goethe-University,Department of Nephrology
[2] Friedrich-Alexander-University,Department of Nephrology
来源：
Basic Research in Cardiology | 2003年 / 98卷
关键词：
Cardiac sensory afferents; mechanosensitive ion channel; conduction velocity; rat;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Recent studies suggest a role of ion channels of the DEG/ENaC family for mechanosensation in different species and in baroreceptor reflex control in rats. We tested the hypothesis that ENaC within the cardiac sensory network are mandatory for mechanosensation. Experiments were performed in male Sprague-Dawley rats, isolated nodose ganglion cells with cardiac afferents and isolated vagus nerves.
引用
收藏
页码：388 / 400
页数：12
相关论文
共 50 条
  • [21] Role of the afferent renal nerves in sodium homeostasis and blood pressure regulation in rats
    Frame, Alissa A.
    Carmichael, Casey Y.
    Kuwabara, Jill T.
    Cunningham, J. Thomas
    Wainford, Richard D.
    EXPERIMENTAL PHYSIOLOGY, 2019, 104 (08) : 1306 - 1323
  • [22] Increased renal α-epithelial sodium channel (ENAC) protein and increased ENAC activity in normal pregnancy
    West, Crystal
    Zhang, Zheng
    Ecker, Geoffrey
    Masilamani, Shyama M. E.
    AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY, 2010, 299 (05) : R1326 - R1332
  • [23] Enhanced expression of epithelial sodium channels in the renal medulla of Dahl S rats
    Amin, Md. Shahrier
    Reza, Erona
    El-Shahat, Esraa
    Wang, Hong-Wei
    Tesson, Frederique
    Leenen, Frans H. H.
    CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY, 2011, 89 (03) : 159 - 168
  • [24] Characterization of a putative amiloride binding domain in the alpha subunit of the epithelial sodium channel (ENaC)
    Appleberry, OK
    Saxena, NC
    Eaton, DC
    FASEB JOURNAL, 2001, 15 (04): : A431 - A431
  • [25] Regulation of blood pressure, the epithelial sodium channel (ENaC), and other key renal sodium transporters by chronic insulin infusion in rats
    Song, J
    Hu, XQ
    Riazi, S
    Tiwari, S
    Wade, JB
    Ecelbarger, CA
    AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY, 2006, 290 (05) : F1055 - F1064
  • [26] Changes in mineralocorticoid receptors (MR) and epithelial sodium channels (ENaC) in rat brain by central sodium
    Wang, Hongwei
    Amin, M. Shahrier
    Tan, Junhui
    Leenen, Frans H. H.
    JOURNAL OF HYPERTENSION, 2006, 24 : 102 - 102
  • [27] Regulation of the Epithelial Sodium Channels (ENaC) by Small G-Proteins and Phosphatidylinositides
    Karpushev, A. V.
    Pavlov, T. S.
    Staruschenko, A. V.
    BIOLOGICHESKIE MEMBRANY, 2009, 26 (04): : 265 - 279
  • [28] Changes in mineralocorticoid receptors (MR) and epithelial sodium channels (ENaC) in rat brain by central sodium
    Wang, Hong-Wei
    Amin, M. Shahrier
    Tan, Junhui
    Leenen, Frans H.
    HYPERTENSION, 2006, 48 (04) : E50 - E51
  • [29] Expression and regulation of epithelial sodium channels (ENaC) by cGMP/PKG in bone and osteoblasts
    Li, Qingnan
    Huang, Jian
    Nie, Hongguang
    Mao, Sufeng
    Zhao, Runzhen
    Han, Dongyun
    Yang, Guozhu
    Lu, Li
    Chen, Jun
    Ji, Honglong
    FASEB JOURNAL, 2009, 23
  • [30] Epithelial sodium channels: Their role in disease
    Rossier, B
    NEWS IN PHYSIOLOGICAL SCIENCES, 1996, 11 : 102 - 102
12345