The Relationship Between DOT1L, Histone H3 Methylation, and Genome Stability in Cancer

被引：0
|
作者：
Brent J. Guppy
Lucile M-P. Jeusset
Kirk J. McManus
机构：
[1] University of Manitoba,Department of Biochemistry & Medical Genetics
[2] CancerCare Manitoba,Research Institute in Oncology and Hematology
来源：
Current Molecular Biology Reports | 2017年 / 3卷 / 1期
关键词：
DOT1L; H3K79me1; H3K79me2; H3K79me3; Genome stability; Cancer;
D O I：
10.1007/s40610-017-0051-0
中图分类号：
学科分类号：
摘要：
引用
收藏
页码：18 / 27
页数：9
相关论文
共 50 条
  • [41] Histone H3 lysine 4 methylation revisited
    Kusch, Thomas
    TRANSCRIPTION-AUSTIN, 2012, 3 (06): : 310 - 314
  • [42] DOT1L is a barrier to histone acetylation during reprogramming to pluripotency
    Wille, Coral K.
    Zhang, Xiaoya
    Haws, Spencer A.
    Denu, John M.
    Sridharan, Rupa
    SCIENCE ADVANCES, 2023, 9 (46)
  • [43] DOT1L inhibition reveals a distinct subset of enhancers dependent on H3K79 methylation
    Laura Godfrey
    Nicholas T. Crump
    Ross Thorne
    I-Jun Lau
    Emmanouela Repapi
    Dimitra Dimou
    Alastair L. Smith
    Joe R. Harman
    Jelena M. Telenius
    A. Marieke Oudelaar
    Damien J. Downes
    Paresh Vyas
    Jim R. Hughes
    Thomas A. Milne
    Nature Communications, 10
  • [44] The Histone Methyltransferase DOT1L Is Essential for Humoral Immune Responses
    Kealy, Liam
    Di Pietro, Andrea
    Hailes, Lauren
    Scheer, Sebastian
    Dalit, Lennard
    Groom, Joanna R.
    Zaph, Colby
    Good-Jacobson, Kim L.
    CELL REPORTS, 2020, 33 (11):
  • [45] DOT1L inhibition reveals a distinct subset of enhancers dependent on H3K79 methylation
    Godfrey, Laura
    Crump, Nicholas T.
    Thorne, Ross
    Lau, I-Jun
    Repapi, Emmanouela
    Dimou, Dimitra
    Smith, Alastair L.
    Harman, Joe R.
    Telenius, Jelena M.
    Oudelaar, A. Marieke
    Downes, Damien J.
    Vyas, Paresh
    Hughes, Jim R.
    Milne, Thomas A.
    NATURE COMMUNICATIONS, 2019, 10 (1)
  • [46] MLL-Rearranged Leukemia Is Dependent on Aberrant H3K79 Methylation by DOT1L
    Bernt, Kathrin M.
    Zhu, Nan
    Sinha, Amit U.
    Vempati, Sridhar
    Faber, Joerg
    Krivtsov, Andrei V.
    Feng, Zhaohui
    Punt, Natalie
    Daigle, Amanda
    Bullinger, Lars
    Pollock, Roy M.
    Richon, Victoria M.
    Kung, Andrew L.
    Armstrong, Scott A.
    CANCER CELL, 2011, 20 (01) : 66 - 78
  • [47] Role of Dot1L and H3K79 methylation in regulating somatic hypermutation of immunoglobulin genes
    Duan, Zhi
    Baughn, Linda B.
    Wang, Xiaohua
    Zhang, Yongwei
    Gupta, Varun
    MacCarthy, Thomas
    Scharff, Matthew D.
    Yu, Guojun
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2021, 118 (29)
  • [48] Histone H3 Mutations in Cancer
    Wan Y.C.E.
    Liu J.
    Chan K.M.
    Current Pharmacology Reports, 2018, 4 (4) : 292 - 300
  • [49] HISTONE H3 TRANSCRIPT STABILITY IN ALFALFA
    KAPROS, T
    ROBERTSON, AJ
    WATERBORG, JH
    PLANT MOLECULAR BIOLOGY, 1995, 28 (05) : 901 - 914
  • [50] Rb targets histone H3 methylation and HP1 to promoters
    Soren J. Nielsen
    Robert Schneider
    Uta-Maria Bauer
    Andrew J. Bannister
    Ashby Morrison
    Donal O'Carroll
    Ron Firestein
    Michael Cleary
    Thomas Jenuwein
    Rafael E. Herrera
    Tony Kouzarides
    Nature, 2001, 412 : 561 - 565
12345