Interaction among NMDA receptor-, NMDA glycine site- and AMPA receptor antagonists in spinally mediated analgesia

被引：0
|
作者：
Tomoki Nishiyama
机构：
[1] The University of Tokyo,From the Department of Anesthesiology
来源：
Canadian Journal of Anaesthesia | 2000年 / 47卷
关键词：
NMDA; NMDA Receptor; AMPA Receptor; NMDA Receptor Antagonist; Excitatory Amino Acid Receptor;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Purpose: The NMDA (N-methyl-D-aspartate) receptor antagonists and the NMDA glycine site antagonists given alone have minimal effects on acute nociception. In contrast, the AMPA (alpha-amino-3-hydroxy-5-methylisoxa-zole-4-propionic acid) receptor antagonists have a major role in acute nociception. We investigated the interactions among these three antagonists in acute nociception.
引用
收藏
页码：693 / 698
页数：5
相关论文
共 50 条
  • [1] Interaction among NMDA receptor-, NMDA glycine site- and AMPA receptor antagonists in spinally mediated analgesia
    Nishiyama, T
    [J]. CANADIAN JOURNAL OF ANAESTHESIA-JOURNAL CANADIEN D ANESTHESIE, 2000, 47 (07): : 693 - 698
  • [2] CAN NOVEL AMPA AND NMDA RECEPTOR ANTAGONISTS INDUCE ANALGESIA
    UCHIKAWA, T
    KIUCHI, Y
    OGUCHI, K
    BENSON, KT
    GOTO, H
    [J]. ANESTHESIOLOGY, 1995, 83 (3A) : A877 - A877
  • [3] Glycine-site NMDA receptor antagonists: An update
    Kulagowski, JJ
    [J]. EXPERT OPINION ON THERAPEUTIC PATENTS, 1996, 6 (10) : 1069 - 1079
  • [4] Antagonists and agonists at the glycine site of the NMDA receptor for therapeutic interventions
    Jansen, M
    Dannhardt, G
    [J]. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2003, 38 (7-8) : 661 - 670
  • [5] ANTAGONISTS OF AMPA/KA AND NMDA (GLYCINE SITE) GLUTAMATE RECEPTORS
    Kadieva, M. G.
    Oganesyan, E. T.
    Zefirova, O. H.
    [J]. PHARMACEUTICAL CHEMISTRY JOURNAL, 2008, 42 (02) : 72 - 80
  • [6] Antagonists of AMPA/KA and NMDA (glycine site) glutamate receptors
    M. G. Kadieva
    É. T. Oganesyan
    O. H. Zefirova
    [J]. Pharmaceutical Chemistry Journal, 2008, 42
  • [7] Differential effects of five glycine site antagonists on NMDA receptor desensitisation
    Molnar, P
    Erdo, SL
    [J]. EUROPEAN JOURNAL OF PHARMACOLOGY, 1996, 311 (2-3) : 311 - 314
  • [8] Evaluation of glycine site antagonists of the NMDA receptor in global cerebral ischaemia
    Hicks, CA
    Ward, MA
    Ragumoorthy, N
    Ambler, SJ
    Dell, CP
    Dobson, D
    O'Neill, MJ
    [J]. BRAIN RESEARCH, 1999, 819 (1-2) : 65 - 74
  • [9] THIOKYNURENATES - A NEW GROUP OF ANTAGONISTS OF THE GLYCINE MODULATORY SITE OF THE NMDA RECEPTOR
    MORONI, F
    ALESIANI, M
    GALLI, A
    MORI, F
    PECORARI, R
    CARLA, V
    CHERICI, G
    PELLICCIARI, R
    [J]. EUROPEAN JOURNAL OF PHARMACOLOGY, 1991, 199 (02) : 227 - 232
  • [10] Novel antagonists of the glycine site of the NMDA receptor - Electrophysiological and biochemical characterisation
    Parsons, CG
    Danysz, W
    Hartmann, S
    Bartmann, A
    Chizh, BA
    McLean, MM
    Headley, PM
    [J]. NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY, 1997, 355 (04) : 97 - 97
12345