Incremental value of rare genetic variants for the prediction of multifactorial diseases

被引:0
|
作者
Raluca Mihaescu
Michael J Pencina
Alvaro Alonso
Kathryn L Lunetta
Susan R Heckbert
Emelia J Benjamin
A Cecile JW Janssens
机构
[1] Erasmus University Medical Center,Department of Epidemiology
[2] Boston University,Department of Biostatistics
[3] Harvard Clinical Research Institute,Division of Epidemiology and Community Health, School of Public Health
[4] University of Minnesota,The National Heart, Lung
[5] and Blood Institute's Framingham Heart Study,Department of Epidemiology
[6] University of Washington,Cardiology and Preventive Medicine Section
[7] Boston University School of Medicine,Department of Epidemiology
[8] Boston University School of Public Health,undefined
[9] Emory University,undefined
[10] Rollins School of Public Health,undefined
来源
关键词
Atrial Fibrillation; Disease Risk; Common Variant; Rare Variant; Risk Prediction;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
相关论文
共 50 条
  • [41] Incorporation of rare genetic variants improved the prediction performance of polygenic risk score
    Xu, Hongyan
    GENETIC EPIDEMIOLOGY, 2020, 44 (05) : 529 - 529
  • [42] Interpretation of results from genetic studies of multifactorial diseases
    Todd, JA
    LANCET, 1999, 354 : SI15 - SI16
  • [43] On the genetic contribution to selected multifactorial diseases with autoimmune characteristics
    Miterski, B
    Epplen, JT
    Gencik, M
    CELLULAR AND MOLECULAR BIOLOGY, 2002, 48 (03) : 331 - 341
  • [44] “Mendelian Code” in the Genetic Structure of Common Multifactorial Diseases
    M. S. Nazarenko
    A. A. Sleptcov
    V. P. Puzyrev
    Russian Journal of Genetics, 2022, 58 : 1159 - 1168
  • [45] "Mendelian Code" in the Genetic Structure of Common Multifactorial Diseases
    Nazarenko, M. S.
    Sleptcov, A. A.
    Puzyrev, V. P.
    RUSSIAN JOURNAL OF GENETICS, 2022, 58 (10) : 1159 - 1168
  • [46] Unraveling the genetic component of multifactorial diseases: Dream or reality
    Clerget-Darpoux, F
    INTERNATIONAL STATISTICAL REVIEW, 2000, 68 (01) : 45 - 51
  • [47] Electrocardiographic Manifestations of Sarcomere Mutations in Hypertrophic Cardiomyopathy: Incremental Value in the Prediction Genetic Risk
    Lakdawala, Neal
    Thune, Jens J.
    Cirino, Allison
    Havndrupm, Ole
    Christiansen, Michael
    Bundgaard, Henning
    MacRae, Calum A.
    Carlsen, Christian M.
    Colan, Steven D.
    Kober, Lars V.
    Ho, Carolyn Y.
    CIRCULATION, 2009, 120 (18) : S566 - S566
  • [48] The role of rare variants in common diseases
    Ludwig, Kerstin U.
    Degenhardt, Franziska
    Noethen, Markus M.
    MEDIZINISCHE GENETIK, 2019, 31 (02) : 212 - 221
  • [49] Prevalence and Significance of Rare Genetic Variants in AKAP9 in Inherited Cardiac Diseases
    Hermida, Alexis
    Ader, Flavie
    Jedraszak, Guillaume
    Viboud, Guillaume
    Fressart, Veronique
    Brehin, Anne-Claire
    Gerard, Marion
    Khraiche, Diala
    Palmyre, Aurelien
    Paziaud, Olivier
    Popescu, Elena
    Proukhnitzky, Julie
    Laredo, Mikael
    Richard, Pascale
    Vedrenne, Geraldine
    Vernier, Agathe
    Charron, Philippe
    Gandjbakhch, Estelle
    CIRCULATION-GENOMIC AND PRECISION MEDICINE, 2024, 17 (01):
  • [50] Identifying Outbreaks of Two Common Degenerative Diseases as a Strategy to Identify Genetic Rare Variants
    Karakachoff, M.
    Persyn, E.
    Simonet, F.
    Le Marec, H.
    Probst, V.
    Le Tourneau, T.
    Tallec, A.
    Redon, R.
    Schott, J. -J.
    Molinaro, S.
    Dina, C.
    HUMAN HEREDITY, 2015, 79 (01) : 39 - 40