Incremental value of rare genetic variants for the prediction of multifactorial diseases

被引：0
|
作者：
Raluca Mihaescu
Michael J Pencina
Alvaro Alonso
Kathryn L Lunetta
Susan R Heckbert
Emelia J Benjamin
A Cecile JW Janssens
机构：
[1] Erasmus University Medical Center,Department of Epidemiology
[2] Boston University,Department of Biostatistics
[3] Harvard Clinical Research Institute,Division of Epidemiology and Community Health, School of Public Health
[4] University of Minnesota,The National Heart, Lung
[5] and Blood Institute's Framingham Heart Study,Department of Epidemiology
[6] University of Washington,Cardiology and Preventive Medicine Section
[7] Boston University School of Medicine,Department of Epidemiology
[8] Boston University School of Public Health,undefined
[9] Emory University,undefined
[10] Rollins School of Public Health,undefined
来源：
Genome Medicine | / 5卷
关键词：
Atrial Fibrillation; Disease Risk; Common Variant; Rare Variant; Risk Prediction;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
相关论文
共 50 条
  • [21] Role of genetic variability in Mendelian and multifactorial diseases
    Ramirez-Bello, Julian
    GACETA MEDICA DE MEXICO, 2019, 155 (05): : 499 - 507
  • [22] Genetic epidemiology and frequent multifactorial diseases.
    Cambien, F
    REVUE D EPIDEMIOLOGIE ET DE SANTE PUBLIQUE, 1996, 44 (06): : 530 - 539
  • [23] Genetic architecture of common multifactorial diseases - Discussion
    Weiss, KM
    Sing, CF
    Bodmer, WF
    Freimer, NB
    Chakravarti, A
    Chakraborty, R
    Templeton, AR
    Harper, PS
    VARIATION IN THE HUMAN GENOME, 1996, 197 : 229 - 232
  • [24] GENETIC-ANALYSIS OF 5 MULTIFACTORIAL DISEASES
    SINGH, SM
    MACKAY, TFC
    ZOUROS, E
    CANADIAN JOURNAL OF GENETICS AND CYTOLOGY, 1975, 17 (03): : 467 - 467
  • [25] Generation of prediction models based on rare and common genetic variants in PD
    Bobbili, D. R.
    Banda, P.
    Krueger, R.
    May, P.
    EUROPEAN JOURNAL OF HUMAN GENETICS, 2019, 27 : 297 - 297
  • [26] Rare variants of pemphigoid diseases
    Yilmaz, Kaan
    Kiehne, Charlotte
    Holtsche, Maike M.
    Schmidt, Enno
    DERMATOLOGIE, 2023, 74 (12): : 937 - 947
  • [27] Multifactorial Rare Diseases: Can Uncertainty Analysis Bring Added Value to the Search for Risk Factors and Etiopathogenesis?
    Taruscio, Domenica
    Mantovani, Alberto
    MEDICINA-LITHUANIA, 2021, 57 (02): : 1 - 14
  • [28] Multivariate Methods for Genetic Variants Selection and Risk Prediction in Cardiovascular Diseases
    Malovini, Alberto
    Bellazzi, Riccardo
    Napolitano, Carlo
    Guffanti, Guia
    FRONTIERS IN CARDIOVASCULAR MEDICINE, 2016, 3
  • [29] Interpreting the pathogenicity of genetic variants in rare diseases: Lessons from Fabry disease
    Germain, Dominique P.
    Levade, Thierry
    Hachulla, Eric
    Knebelmann, Bertrand
    Lacombe, Didier
    Rabes, Jean-Pierre
    MOLECULAR GENETICS AND METABOLISM, 2022, 135 (02) : S45 - S45
  • [30] Common genetic variants contribute more to rare diseases than previously thought
    Breen, Gerome
    NATURE, 2024, : 304 - 305
12345