Multicenter research priorities in pediatric CMR: results of a collaborative wiki survey

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作者
Rebecca S. Beroukhim
Anthony Merlocco
Jennifer F. Gerardin
Edythe Tham
Jyoti K. Patel
Saira Siddiqui
Benjamin Goot
Kanwal Farooqi
Jonathan Soslow
Heynric Grotenhuis
Kan Hor
Vivek Muthurangu
Francesca Raimondi
机构
[1] Boston Children’s Hospital,Department of Cardiology, Harvard Medical School
[2] Le Bonheur Children’s Hospital,Department of Cardiology, University of Tennessee Health Science Center
[3] Children’s Hospital of Wisconsin,Division of Pediatric Cardiology, Medical College of Wisconsin
[4] University of Alberta,Department of Pediatrics, Stollery Children’s Hospital
[5] Riley Hospital for Children at Indiana University Health,Division of Cardiology, Department of Pediatrics
[6] Atlantic Health System,Division of Pediatric Cardiology
[7] New York Presbyterian-Morgan Stanley Children’s Hospital,Division of Pediatric Cardiology, Department of Pediatrics, Columbia University Medical Center
[8] Vanderbilt University,Division of Pediatric Cardiology, Department of Pediatrics
[9] Utrecht Medical Center,Department of Pediatric Cardiology
[10] Ohio State University,Department of Pediatrics, The Heart Center, Nationwide Children’s Hospital
[11] University College London,Department of Cardiology, UCL Center for Translational Cardiovascular Imaging
[12] University of Florence,Department of Cardiology, Meyer Children’s Hospital
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摘要
Multicenter studies in pediatric cardiovascular magnetic resonance (CMR) improve statistical power and generalizability. However, a structured process for identifying important research topics has not been developed. We aimed to (1) develop a list of high priority knowledge gaps, and (2) pilot the use of a wiki survey to collect a large group of responses. Knowledge gaps were defined as areas that have been either unexplored or under-explored in the research literature. High priority goals were: (1) feasible and answerable from a multicenter research study, and (2) had potential for high impact on the field of pediatric CMR. Seed ideas were contributed by a working group and imported into a pairwise wiki survey format which allows for new ideas to be uploaded and voted upon (https://allourideas.org). Knowledge gaps were classified into 2 categories: ‘Clinical CMR Practice’ (16 ideas) and ‘Disease Specific Research’ (22 ideas). Over a 2-month period, 3,658 votes were cast by 96 users, and 2 new ideas were introduced. The 3 highest scoring sub-topics were myocardial disorders (9 ideas), translating new technology & techniques into clinical practice (7 ideas), and normal reference values (5 ideas). The highest priority gaps reflected strengths of CMR (e.g., myocardial tissue characterization; implementation of technologic advances into clinical practice), and deficiencies in pediatrics (e.g., data on normal reference values). The wiki survey format was effective and easy to implement, and could be used for future surveys.
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