Chirality and Drugs Used in Psychiatry: Nice to Know or Need to Know?

被引：0

作者：

Roger M. Lane

Glen B. Baker

机构：

[1] Pfizer Inc.,Neurochemical Research Unit Department, Psychiatry Mackenzie Centre

[2] University of Alberta,undefined

来源：

Cellular and Molecular Neurobiology | 1999年 / 19卷

关键词：

enantiomers; racemic; chiral; stereoselective; pharmacokinetics; cytochrome P450; geometric isomers;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

1. Many drugs used to treat psychiatric disorders contain a chiral center or a center of unsaturation and are marketed as a mixture of the resultant enantiomers or geometric isomers, respectively. These enantiomers or geometric isomers may differ markedly with regard to their pharmacodynamic and/or pharmacokinetic properties.

引用

页码：355 / 372

页数：17

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