Chirality and Drugs Used in Psychiatry: Nice to Know or Need to Know?

被引：0

作者：

Roger M. Lane

Glen B. Baker

机构：

[1] Pfizer Inc.,Neurochemical Research Unit Department, Psychiatry Mackenzie Centre

[2] University of Alberta,undefined

来源：

Cellular and Molecular Neurobiology | 1999年 / 19卷

关键词：

enantiomers; racemic; chiral; stereoselective; pharmacokinetics; cytochrome P450; geometric isomers;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

1. Many drugs used to treat psychiatric disorders contain a chiral center or a center of unsaturation and are marketed as a mixture of the resultant enantiomers or geometric isomers, respectively. These enantiomers or geometric isomers may differ markedly with regard to their pharmacodynamic and/or pharmacokinetic properties.

引用

页码：355 / 372

页数：17

共 50 条

[31] No need to know
Frise, Matthew
[J]. PHILOSOPHICAL STUDIES, 2017, 174 (02) : 391 - 401
[32] No need to know
Matthew Frise
[J]. Philosophical Studies, 2017, 174 : 391 - 401
[33] NEED TO KNOW
Conn, David R.
[J]. LIBRARY JOURNAL, 2017, 142 (13) : 46 - 48
[34] The need to know
Young, Roxanne K.
[J]. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2007, 297 (08): : 787 - 788
[35] The need to know
不详
[J]. NEW SCIENTIST, 2008, 199 (2663) : 5 - 5
[36] NEED TO KNOW
HAINES, GE
[J]. NEW SCIENTIST, 1993, 139 (1891) : 48 - 48
[37] A NEED TO KNOW
LUNTZ, JD
[J]. NUCLEONICS, 1953, 11 (01): : 5 - 5
[38] THE NEED TO KNOW
不详
[J]. DATA PROCESSOR-WHITE PLAINS, 1980, 23 (03): : 16 - 21
[39] Need to know
[J]. Printweek, 2005, (41):
[40] Need to know
McIntyre, Karen
[J]. Nonwovens Industry, 2019, 50 (06):

← 1 2 3 4 5 →