Chirality and Drugs Used in Psychiatry: Nice to Know or Need to Know?

被引：0
|
作者：
Roger M. Lane
Glen B. Baker
机构：
[1] Pfizer Inc.,Neurochemical Research Unit Department, Psychiatry Mackenzie Centre
[2] University of Alberta,undefined
来源：
Cellular and Molecular Neurobiology | 1999年 / 19卷
关键词：
enantiomers; racemic; chiral; stereoselective; pharmacokinetics; cytochrome P450; geometric isomers;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
1. Many drugs used to treat psychiatric disorders contain a chiral center or a center of unsaturation and are marketed as a mixture of the resultant enantiomers or geometric isomers, respectively. These enantiomers or geometric isomers may differ markedly with regard to their pharmacodynamic and/or pharmacokinetic properties.
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页码：355 / 372
页数：17
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