Increased erythromycin production by alginate as a medium ingredient or immobilization support in cultures of Saccharopolyspora erythraea

被引：0
|
作者：
J. Hamedi
F. Khodagholi
A. Hassani-Nasab
机构：
[1] University of Tehran,Microbial Biotechnology Laboratory, Department of Biology, Faculty of Science
来源：
Biotechnology Letters | 2005年 / 27卷
关键词：
alginate; erythromycin; immobilization; shear;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Erythromycin production by Saccharopolyspora erythraea immobilized in 2% (w/v) calcium alginate or grown in medium containing 20 g sodium alginate/l inoculated with free cells was almost twice more than that of the control. S. erythraea did not consume alginate, agar, dextran, silicon antifoaming agent or cyclodextrin as a carbon source, although, all of these increased the production of erythromycin. Highest titer of erythromycin (2.3 times more than that of the control) was achieved in medium containing 1 g agar/l.
引用
收藏
页码：661 / 664
页数：3
相关论文
共 50 条
  • [31] Two amino acids missing of MtrA resulted in increased erythromycin level and altered phenotypes in Saccharopolyspora erythraea
    Qian Pan
    Yanbin Tong
    Ya-Jie Han
    Bang-Ce Ye
    Applied Microbiology and Biotechnology, 2019, 103 : 4539 - 4548
  • [32] Production of 6-deoxy-13-cyclopropyl-erythromycin B by Saccharopolyspora erythraea NRRL 18643
    Brown, MS
    Dirlam, JP
    McArthur, HAI
    McCormick, EL
    Morse, BK
    Murphy, PA
    O'Connell, TN
    Pacey, M
    Rescek, DM
    Ruddock, J
    Wax, RG
    JOURNAL OF ANTIBIOTICS, 1999, 52 (08): : 742 - 747
  • [33] Two amino acids missing of MtrA resulted in increased erythromycin level and altered phenotypes in Saccharopolyspora erythraea
    Pan, Qian
    Tong, Yanbin
    Han, Ya-Jie
    Ye, Bang-Ce
    APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, 2019, 103 (11) : 4539 - 4548
  • [34] SACE_5599, a putative regulatory protein, is involved in morphological differentiation and erythromycin production in Saccharopolyspora erythraea
    Kirm, Benjamin
    Magdevska, Vasilka
    Tome, Miha
    Horvat, Marinka
    Karnicar, Katarina
    Petek, Marko
    Vidmar, Robert
    Baebler, Spela
    Jamnik, Polona
    Fujs, Stefan
    Horvat, Jaka
    Fonovic, Marko
    Turk, Boris
    Gruden, Kristina
    Petkovic, Hrvoje
    Kosec, Gregor
    MICROBIAL CELL FACTORIES, 2013, 12
  • [35] Dissecting and engineering of the TetR family regulator SACE_7301 for enhanced erythromycin production in Saccharopolyspora erythraea
    Hang Wu
    Meng Chen
    Yongrong Mao
    Weiwei Li
    Jingtao Liu
    Xunduan Huang
    Ying Zhou
    Bang-Ce Ye
    Lixin Zhang
    David T Weaver
    Buchang Zhang
    Microbial Cell Factories, 13
  • [36] Dissecting and engineering of the TetR family regulator SACE_7301 for enhanced erythromycin production in Saccharopolyspora erythraea
    Wu, Hang
    Chen, Meng
    Mao, Yongrong
    Li, Weiwei
    Liu, Jingtao
    Huang, Xunduan
    Zhou, Ying
    Ye, Bang-Ce
    Zhang, Lixin
    Weaver, David T.
    Zhang, Buchang
    MICROBIAL CELL FACTORIES, 2014, 13 : 1 - 11
  • [37] Inactivation of SACE_3446, a TetR family transcriptional regulator, stimulates erythromycin production in Saccharopolyspora erythraea
    Wu, Hang
    Wang, Yansheng
    Yuan, Li
    Mao, Yongrong
    Wang, Weiwei
    Zhu, Lin
    Wu, Panpan
    Fu, Chengzhang
    Mueller, Rolf
    Weaver, David T.
    Zhang, Lixin
    Zhang, Buchang
    SYNTHETIC AND SYSTEMS BIOTECHNOLOGY, 2016, 1 (01) : 39 - 46
  • [38] Effect of small scale culture vessel type on hyphal fragment size and erythromycin production in Saccharopolyspora erythraea
    Bushell, ME
    Dunstan, GL
    Wilson, GC
    BIOTECHNOLOGY LETTERS, 1997, 19 (09) : 849 - 852
  • [39] Optimization of Process Parameters for Erythromycin Production Under Solid State Fermentation by Saccharopolyspora erythraea NCIMB 12462
    El Deen, Azza M. Noor
    Abdelwahed, Nayera A. M.
    Shata, Hoda M. A.
    Farid, Mohamed A. M.
    JOURNAL OF PURE AND APPLIED MICROBIOLOGY, 2015, 9 (01): : 41 - 48
  • [40] SACE_5599, a putative regulatory protein, is involved in morphological differentiation and erythromycin production in Saccharopolyspora erythraea
    Benjamin Kirm
    Vasilka Magdevska
    Miha Tome
    Marinka Horvat
    Katarina Karničar
    Marko Petek
    Robert Vidmar
    Špela Baebler
    Polona Jamnik
    Štefan Fujs
    Jaka Horvat
    Marko Fonovič
    Boris Turk
    Kristina Gruden
    Hrvoje Petković
    Gregor Kosec
    Microbial Cell Factories, 12
12345