Increased erythromycin production by alginate as a medium ingredient or immobilization support in cultures of Saccharopolyspora erythraea

被引：0
|
作者：
J. Hamedi
F. Khodagholi
A. Hassani-Nasab
机构：
[1] University of Tehran,Microbial Biotechnology Laboratory, Department of Biology, Faculty of Science
来源：
Biotechnology Letters | 2005年 / 27卷
关键词：
alginate; erythromycin; immobilization; shear;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Erythromycin production by Saccharopolyspora erythraea immobilized in 2% (w/v) calcium alginate or grown in medium containing 20 g sodium alginate/l inoculated with free cells was almost twice more than that of the control. S. erythraea did not consume alginate, agar, dextran, silicon antifoaming agent or cyclodextrin as a carbon source, although, all of these increased the production of erythromycin. Highest titer of erythromycin (2.3 times more than that of the control) was achieved in medium containing 1 g agar/l.
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页码：661 / 664
页数：3
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