user

Lipid peroxidation in erythrocytes of patients with type 2 diabetes mellitus

被引：6
|
作者：
P. Ashok Kumar
G. Rajagopal
机构：
[1] Annamalai University,Department of Biochemistry, Rajah Muthiah Medical College
来源：
Indian Journal of Clinical Biochemistry | 2003年 / 18卷 / 1期
关键词：
Glutathione; Type 2 Diabetes; Catalase; Peroxidase; Superoxide Dismutase;
D O I：
10.1007/BF02867668
中图分类号：
学科分类号：
摘要：
Lipid peroxidation by measurement of Thiobarbituric Acid Reactive Substances (TBARS) and antioxidant status by determining the activities of the enzymes, Catalase (Cat), Glutathione Peroxidase (GPx) and Superoxide Dismutase (SOD) and the level of Reduced Glutathione (GSH) in the erythrocytes of patients with type 2 Diabetes Mellitus were investigated. It was observed that the level of TBARS in the erythrocytes was increased by 50% showing a significant generation of free radicals in the erythrocytes of these patients. The activities of both Cat and SOD were enhanced while that of GPx was not altered. The level of GSH was also not changed.
引用
收藏
页码：71 / 74
页数：3
相关论文
共 50 条
  • [41] Serum lipid peroxidation potential as a biomarker for risk-stratification of coronary artery disease in patients with type 2 diabetes mellitus
    Sugur, Kavya
    Kempegowda, Swetha N.
    Shambu, Sunil K.
    Mahadevappa, Manjappa
    Kengegowda, Vinay K.
    Gowda, Jadeppa
    Thimmulappa, Rajesh K.
    DIABETES & METABOLIC SYNDROME-CLINICAL RESEARCH & REVIEWS, 2024, 18 (10)
  • [42] Type 2 Diabetes Mellitus and Lipid Abnormalities
    Shaikh, Mumtaz Ali
    Kumar, Santosh
    Ghouri, Rafi Ahmed
    JOURNAL OF THE LIAQUAT UNIVERSITY OF MEDICAL AND HEALTH SCIENCES, 2010, 9 (03): : 145 - 147
  • [43] Lipid peroxidation marker in saliva of Type 2 Diabetes Mellitus with oral manifestations - A Clinical and biochemical study
    Madi, M.
    Babu, S. G.
    Kumari, S.
    Shetty, S. R.
    Bhat, S.
    Castelino
    BANGLADESH JOURNAL OF MEDICAL SCIENCE, 2018, 17 (04): : 644 - 651
  • [44] Evaluation of the effect of diabetes control on lipid profiles and lipid peroxidation in patients with type II diabetes
    Parsaeian, Nayereh
    Jalali, Bemanali
    CLINICAL BIOCHEMISTRY, 2011, 44 (13) : S130 - S130
  • [45] Vascular Disaggregation Effects On Erythrocytes In Patients With Arterial Hypertension With Type 2 Diabetes Mellitus
    Medvedev, I. N.
    RESEARCH JOURNAL OF PHARMACEUTICAL BIOLOGICAL AND CHEMICAL SCIENCES, 2018, 9 (03): : 1193 - 1197
  • [46] Expression Of Spontaneous Aggregation Of Erythrocytes In Patients With Arterial Hypertension With Type 2 Diabetes Mellitus
    Medvedev, I. N.
    RESEARCH JOURNAL OF PHARMACEUTICAL BIOLOGICAL AND CHEMICAL SCIENCES, 2018, 9 (05): : 1448 - 1452
  • [47] CHARACTERISTICS OF ERYTHROCYTES AND HEMOGLOBIN IN PATIENTS WITH ISCHEMIC HEART DISEASE AND TYPE 2 DIABETES MELLITUS
    Gorokhova, S. G.
    Atamanova, M. A.
    TERAPEVTICHESKII ARKHIV, 2008, 80 (10) : 16 - 21
  • [48] Evaluation of aldehyde dehydrogenase from human erythrocytes of patients with type 2 diabetes mellitus
    Picazo, A.
    Jimenez-Osorio, A. S.
    Pedraza-Chaverri, J.
    Ramirez-Arellano, E.
    Monroy, A.
    Barrera-Oviedo, D.
    DIABETOLOGIA, 2015, 58 : S137 - S137
  • [49] Effect of Metformin or Gliclazide on Lipid Peroxidation and Antioxidant Levels in Patients with Diabetes Mellitus
    Memisogullari, Ramazan
    Tuerkeli, Mehmet
    Bakan, Ebubekir
    Akcay, Fatih
    TURKISH JOURNAL OF MEDICAL SCIENCES, 2008, 38 (06) : 545 - 548
  • [50] LIPID PEROXIDATION PRODUCTS AND ENDOGENOUS INTOXICATION LEVELS IN PATIENTS WITH TYPE 1 DIABETES MELLITUS AND DIFFERENT STAGES OF ALBUMINURIA
    Darenskaya, M.
    Kolesnikov, S.
    Chugunova, E.
    Semenova, N.
    Kolesnikova, L.
    DIABETES TECHNOLOGY & THERAPEUTICS, 2023, 25 : A200 - A200
12345