A three-dimensional human neural cell culture model of Alzheimer’s disease

被引：0
|
作者：
Se Hoon Choi
Young Hye Kim
Matthias Hebisch
Christopher Sliwinski
Seungkyu Lee
Carla D’Avanzo
Hechao Chen
Basavaraj Hooli
Caroline Asselin
Julien Muffat
Justin B. Klee
Can Zhang
Brian J. Wainger
Michael Peitz
Dora M. Kovacs
Clifford J. Woolf
Steven L. Wagner
Rudolph E. Tanzi
Doo Yeon Kim
机构：
[1] Genetics and Aging Research Unit,Division of Mass Spectrometry Research
[2] MassGeneral Institute for Neurodegenerative Disease,Department of Neurosciences
[3] Massachusetts General Hospital,undefined
[4] Harvard Medical School,undefined
[5] Korea Basic Science Institute,undefined
[6] Cheongju-si,undefined
[7] Chungbuk 363-883,undefined
[8] South Korea,undefined
[9] Institute of Reconstructive Neurobiology,undefined
[10] Life and Brain Center,undefined
[11] University of Bonn and Hertie Foundation,undefined
[12] 53127 Bonn,undefined
[13] Germany,undefined
[14] FM Kirby Neurobiology Center,undefined
[15] Boston Children’s Hospital and Harvard Stem Cell Institute,undefined
[16] The Whitehead Institute for Biomedical Research,undefined
[17] University of California,undefined
[18] San Diego,undefined
[19] La Jolla,undefined
[20] California 92093,undefined
[21] USA,undefined
来源：
Nature | 2014年 / 515卷
关键词：
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Early-onset familial Alzheimer’s disease mutations induce both amyloid-β and tau pathologies in differentiated human neural stem cells in 3D cultures.
引用
收藏
页码：274 / 278
页数：4
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