The long isoform uncoupling protein-3 (UCP3L) in human energy homeostasis

被引：0
|
作者：
WK Chung
A Luke
RS Cooper
C Rotini
A Vidal-Puig
M Rosenbaum
D Gordon
SM Leal
S Caprio
R Goldsmith
AL Andreu
C Bruno
S DiMauro
M Heo
WL Lowe
BB Lowell
DB Allison
RL Leibel
机构：
[1] Columbia University,Departments of Pediatrics and Medicine, Division of Molecular Genetics
[2] College of Physicians and Surgeons,Department of Preventive Medicine and Epidemiology
[3] Naomi Berrie Diabetes Center,Division of Endocrinology
[4] Russ Berrie Medical Science Pavilion,Division of Pediatric Endocrinology
[5] Loyola University Medical Center,Department of Medicine
[6] Beth Israel-Deaconess Medical Center,undefined
[7] The Rockefeller University,undefined
[8] Yale University School of Medicine,undefined
[9] St Luke’s / Roosevelt Hospital Center,undefined
[10] Obesity Research Center,undefined
[11] Columbia University College of Physicians and Surgeons,undefined
[12] Northwestern University School of Medicine,undefined
[13] Columbia University College of Physicians & Surgeons,undefined
[14] H. Houston Merritt Clinical Research Centre for Muscular Dystrophy and Related Diseases,undefined
来源：
International Journal of Obesity | 1999年 / 23卷
关键词：
obesity; diabetes; skeletal muscle; thermogenesis;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
The biological role(s) proposed for UCP3 in energy homeostasis have been based primarily upon amino acid sequence homology to UCP1. Spontaneous mutations of UCP3 have been described in humans, but not in rodents. The functional consequences—or lack thereof—of these mutations in humans will be of great importance in elucidating the biology of this protein. The results of two such studies are summarized here.
引用
收藏
页码：S49 / S50
相关论文
共 50 条
  • [1] The long isoform uncoupling protein-3 (UCP3L) in human energy homeostasis
    Chung, WK
    Luke, A
    Cooper, RS
    Rotini, C
    Vidal-Puig, A
    Rosenbaum, M
    Gordon, D
    Leal, SM
    Caprio, S
    Goldsmith, R
    Andreu, AL
    Bruno, C
    DiMauro, S
    Heo, M
    Lowe, WL
    Lowell, BB
    Allison, DB
    Leibel, RL
    INTERNATIONAL JOURNAL OF OBESITY, 1999, 23 (Suppl 6) : S49 - S50
  • [2] Uncoupling protein-3 (UCP3): A mitochondrial carrier in search of a function
    Lowell, BB
    INTERNATIONAL JOURNAL OF OBESITY, 1999, 23 (Suppl 6) : S43 - S45
  • [3] Uncoupling protein-3 (UCP3): A mitochondrial carrier in search of a function
    BB Lowell
    International Journal of Obesity, 1999, 23 : S43 - S45
  • [4] Uncoupling protein-2 (UCP2) and uncoupling protein-3 (UCP3) expression in adipose tissue and skeletal muscle in humans
    D Langin
    D Larrouy
    P Barbe
    L Millet
    N Viguerie-Bascands
    F Andreelli
    M Laville
    H Vidal
    International Journal of Obesity, 1999, 23 : S64 - S67
  • [5] Uncoupling protein-2 (UCP2) and uncoupling protein-3 (UCP3) expression in adipose tissue and skeletal muscle in humans
    Langin, D
    Larrouy, D
    Barbe, P
    Millet, L
    Viguerie-Bascands, N
    Andreelli, F
    Laville, M
    Vidal, H
    INTERNATIONAL JOURNAL OF OBESITY, 1999, 23 (Suppl 6) : S64 - S67
  • [6] Absence of Uncoupling Protein-3 at Thermoneutrality Impacts Lipid Handling and Energy Homeostasis in Mice
    Lombardi, Assunta
    Busiello, Rosa Anna
    De Matteis, Rita
    Lionetti, Lilla
    Savarese, Sabrina
    Moreno, Maria
    Gentile, Alessandra
    Silvestri, Elena
    Senese, Rosalba
    de Lange, Pieter
    Cioffi, Federica
    Lanni, Antonia
    Goglia, Fernando
    CELLS, 2019, 8 (08)
  • [7] Human uncoupling protein-3 and obesity: An update
    Hesselink, MKC
    Mensink, M
    Schrauwen, P
    OBESITY RESEARCH, 2003, 11 (12): : 1429 - 1443
  • [8] Tissue specific regulation of uncoupling protein-3 (UCP3) and UCP2 gene expression in rat models of obesity
    Matsuda, J
    Itoh, H
    Son, C
    Doi, K
    Tanaka, T
    Fukunaga, Y
    Shintani, M
    Inoue, G
    Hosoda, K
    DIABETES, 1998, 47 : A431 - A431
  • [9] Properties of the human long and short isoforms of the uncoupling protein-3 expressed in yeast cells
    Hinz, W
    Grüninger, S
    De Pover, A
    Chiesi, M
    FEBS LETTERS, 1999, 462 (03) : 411 - 415
  • [10] Genetic and physiologic analysis of the role of uncoupling protein 3 in human energy homeostasis
    Chung, WK
    Luke, A
    Cooper, RS
    Rotini, C
    Vidal-Puig, A
    Rosenbaum, M
    Chua, M
    Solanes, G
    Zheng, M
    Zhao, L
    LeDuc, C
    Eisberg, A
    Chu, F
    Murphy, E
    Schreier, M
    Aronne, L
    Caprio, S
    Kahle, B
    Gordon, D
    Leal, SM
    Goldsmith, R
    Andreu, AL
    Bruno, C
    DiMauro, S
    Heo, MS
    Lowe, WL
    Lowell, BB
    Allison, DB
    Leibel, RL
    DIABETES, 1999, 48 (09) : 1890 - 1895
12345