Cleavage of cohesin rings coordinates the separation of centrioles and chromatids

被引：0
|
作者：
Laura Schöckel
Martin Möckel
Bernd Mayer
Dominik Boos
Olaf Stemmann
机构：
[1] University of Bayreuth,
[2] Cancer Research UK,undefined
[3] Clare Hall Laboratories,undefined
来源：
Nature Cell Biology | 2011年 / 13卷
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学科分类号：
摘要：
While separase is implicated in centrosome disjunction as well as in chromosome separation, its precise role at the centrosome has been uncertain. The proteolytic activity of separase is demonstrated to induce centriole disengagement through cleavage of cohesin.
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页码：966 / 972
页数：6
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