Cleavage of cohesin rings coordinates the separation of centrioles and chromatids

被引：0
|
作者：
Laura Schöckel
Martin Möckel
Bernd Mayer
Dominik Boos
Olaf Stemmann
机构：
[1] University of Bayreuth,
[2] Cancer Research UK,undefined
[3] Clare Hall Laboratories,undefined
来源：
Nature Cell Biology | 2011年 / 13卷
关键词：
D O I：
暂无
中图分类号：
学科分类号：
摘要：
While separase is implicated in centrosome disjunction as well as in chromosome separation, its precise role at the centrosome has been uncertain. The proteolytic activity of separase is demonstrated to induce centriole disengagement through cleavage of cohesin.
引用
收藏
页码：966 / 972
页数：6
相关论文
共 50 条
  • [11] Structural basis of cohesin cleavage by separase
    Zhonghui Lin
    Xuelian Luo
    Hongtao Yu
    Nature, 2016, 532 : 131 - 134
  • [12] How are cohesin rings opened and closed?
    Shintomi, Keishi
    Hirano, Tatsuya
    TRENDS IN BIOCHEMICAL SCIENCES, 2007, 32 (04) : 154 - 157
  • [13] Leukemogenic Activity of Cohesin Rings True
    Williams, Mark S.
    Somervaille, Tim C. P.
    CELL STEM CELL, 2015, 17 (06) : 642 - 644
  • [14] Absence of mouse REC8 cohesin promotes synapsis of sister chromatids in meiosis
    Xu, HL
    Beasley, MD
    Warren, WD
    van der Horst, GTJ
    McKay, MJ
    DEVELOPMENTAL CELL, 2005, 8 (06) : 949 - 961
  • [15] Sister-chromatid separation at anaphase onset is promoted by cleavage of the cohesin subunit Scc1
    Frank Uhlmann
    Friedrich Lottspeich
    Kim Nasmyth
    Nature, 1999, 400 : 37 - 42
  • [16] Sister-chromatid separation at anaphase onset is promoted by cleavage of the cohesin subunit Scc1
    Uhlmann, F
    Lottspeich, F
    Nasmyth, K
    NATURE, 1999, 400 (6739) : 37 - 42
  • [17] DNA-dependent cohesin cleavage by separase
    Kucej, Martin
    Zou, Hui
    NUCLEUS, 2010, 1 (01) : 4 - 7
  • [18] Cohesin cleavage is insufficient for centriole disengagement in Drosophila
    Oliveira, Raquel A.
    Nasmyth, Kim
    CURRENT BIOLOGY, 2013, 23 (14) : R601 - R603
  • [19] Spo13 regulates cohesin cleavage
    Lee, BH
    Amon, A
    Prinz, S
    GENES & DEVELOPMENT, 2002, 16 (13) : 1672 - 1681
  • [20] Cohesin cleavage by separase is enhanced by a substrate motif distinct from the cleavage site
    Rosen, Laura E.
    Klebba, Joseph E.
    Asfaha, Jonathan B.
    Ghent, Chloe M.
    Campbell, Melody G.
    Cheng, Yifan
    Morgan, David O.
    NATURE COMMUNICATIONS, 2019, 10 (1)
12345