Synthesis and Cytotoxic Activity of 1,2,3-Triazole Derivatives in Glioma Cell Cultures

被引：0
|
作者：
I. S. Khazhieva
T. V. Glukhareva
O. S. El’tsov
Yu. Yu. Morzherin
A. A. Minin
V. A. Pozdina
M. V. Ulitko
机构：
[1] First President of Russia B. N. El’tsin Urals Federal University,
来源：
Pharmaceutical Chemistry Journal | 2015年 / 49卷
关键词：
1,2,3-triazoles; diazo compounds; regrouping; biological activity; cytotoxicity; glioma; cell cultures; IC;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
A series of 1,2,3-triazole derivatives was prepared and their cytotoxic actions on glioma cell cultures were studied. Amethod for the synthesis of 1-R-5-methyl-1H-[1,2,3]triazole-4-carboxamides is presented, based on transformation of 4-acetyl-1-phenyl-1H-[1,2,3]-triazolate sodium using primary amine hydrochlorides.
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页码：296 / 300
页数：4
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