Synthesis of imidazo[1,2-a]pyrazine and imidazo[1,2-a]pyrimidine derivatives

被引：0
|
作者：
A. V. Borisov
A. A. Tolmachev
O. A. Zavada
I. A. Zhuravel’
S. N. Kovalenko
机构：
[1] Enamine Ltd,Institute of Organic Chemistry
[2] National Academy of Sciences of Ukraine,undefined
[3] National University of Pharmacy,undefined
来源：
Chemistry of Heterocyclic Compounds | 2013年 / 49卷
关键词：
2-aminoimidazole; imidazo[1,2-; ]pyrazines; imidazo[1,2-; ]pyrimidines; catalytic hydro-genation;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Synthetic approaches to the construction of bicyclic systems containing the imidazole nucleus have been considered. Methods for obtaining derivatives of imidazo[1,2-a]pyrazine and imidazo[1,2-a]pyrimidine have been studied, and methods have been developed for catalytic hydrogenation of these compounds. Partial reduction of the imidazole ring on imidazo[1,2-a]pyrimidine hydrogenation has been discovered for the first time.
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页码：704 / 711
页数：7
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