An efficient transformation of methyl ethers and nitriles to amides catalyzed by Iron(III) perchlorate hydrate

被引：0

作者：

Guibo Yin

Bin Yan

Junqing Chen

Min Ji

机构：

[1] Jiangsu College of Engineering and Technology,Institute of Pharmaceutical Engineering

[2] Southeast University,School of Biological Sciences and Medical Engineering

来源：

Journal of the Iranian Chemical Society | 2019年 / 16卷

关键词：

Ritter reaction; Methyl ethers; Fe(ClO; ); ·H; O; Amides;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

An efficient and inexpensive synthesis of N-substituted amides from the reaction of nitriles with methyl ethers catalyzed by Fe(ClO4)3·H2O is described. Fe(ClO4)3·H2O is an economically efficient catalyst for the Ritter Reaction under solvent-free conditions. A range of methyl ethers (benzyl, sec-alkyl and tert-butyl ethers) were reacted with nitriles to provide the corresponding amides in high–excellent yields.

引用

页码：1355 / 1363

页数：8

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