An efficient transformation of methyl ethers and nitriles to amides catalyzed by Iron(III) perchlorate hydrate

被引：0
|
作者：
Guibo Yin
Bin Yan
Junqing Chen
Min Ji
机构：
[1] Jiangsu College of Engineering and Technology,Institute of Pharmaceutical Engineering
[2] Southeast University,School of Biological Sciences and Medical Engineering
来源：
Journal of the Iranian Chemical Society | 2019年 / 16卷
关键词：
Ritter reaction; Methyl ethers; Fe(ClO; ); ·H; O; Amides;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
An efficient and inexpensive synthesis of N-substituted amides from the reaction of nitriles with methyl ethers catalyzed by Fe(ClO4)3·H2O is described. Fe(ClO4)3·H2O is an economically efficient catalyst for the Ritter Reaction under solvent-free conditions. A range of methyl ethers (benzyl, sec-alkyl and tert-butyl ethers) were reacted with nitriles to provide the corresponding amides in high–excellent yields.
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页码：1355 / 1363
页数：8
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