Massive restructuring of neuronal circuits during functional reorganization of adult visual cortex

被引:0
|
作者
Tara Keck
Thomas D Mrsic-Flogel
Miguel Vaz Afonso
Ulf T Eysel
Tobias Bonhoeffer
Mark Hübener
机构
[1] Max Planck Institute of Neurobiology,Department of Neurophysiology
[2] Am Klopfersptiz 18,undefined
[3] Ruhr University Bochum,undefined
[4] Present address: Department of Physiology,undefined
[5] University College London,undefined
[6] 21 University Street,undefined
[7] London,undefined
[8] WC1E 6JJ,undefined
[9] UK.,undefined
来源
Nature Neuroscience | 2008年 / 11卷
关键词
D O I
暂无
中图分类号
学科分类号
摘要
Following a retinal lesion, it is known that extensive topographical remapping occurs in visual cortex. To examine the dynamics of this plasticity, Keck et al. combined chronic intrinsic and two-photon imaging to follow both the functional and structural modifications of the affected cortical region. They observed close to a complete turnover of spines on the functionally relevant cells, suggesting that a massive rewiring had occurred, producing new circuits.
引用
收藏
页码:1162 / 1167
页数:5
相关论文
共 50 条
  • [1] Massive restructuring of neuronal circuits during functional reorganization of adult visual cortex
    Keck, Tara
    Mrsic-Flogel, Thomas D.
    Afonso, Miguel Vaz
    Eysel, Ulf T.
    Bonhoeffer, Tobias
    Huebener, Mark
    [J]. NATURE NEUROSCIENCE, 2008, 11 (10) : 1162 - 1167
  • [2] Adult neurogenesis and functional plasticity in neuronal circuits
    Pierre-Marie Lledo
    Mariana Alonso
    Matthew S. Grubb
    [J]. Nature Reviews Neuroscience, 2006, 7 : 179 - 193
  • [3] Adult neurogenesis and functional plasticity in neuronal circuits
    Lledo, PM
    Alonso, M
    Grubb, MS
    [J]. NATURE REVIEWS NEUROSCIENCE, 2006, 7 (03) : 179 - 193
  • [4] Action and learning shape the activity of neuronal circuits in the visual cortex
    Pakan, Janelle M. P.
    Francioni, Valerio
    Rochefort, Nathalie L.
    [J]. CURRENT OPINION IN NEUROBIOLOGY, 2018, 52 : 88 - 97
  • [5] Focal activation of neuronal circuits induced by microstimulation in the visual cortex
    Tanaka, Yuta
    Nomoto, Tomohiro
    Shiki, Takuya
    Sakata, Yuya
    Shimada, Yoshinori
    Hayashida, Yuki
    Yagi, Tetsuya
    [J]. JOURNAL OF NEURAL ENGINEERING, 2019, 16 (03)
  • [6] Assessing functional reorganization in visual cortex with simulated retinal lesions
    Holly D. H. Brown
    André D. Gouws
    Richard J. W. Vernon
    Samuel J. D. Lawrence
    Gemma Donnelly
    Lorraine Gill
    Richard P. Gale
    Heidi A. Baseler
    Antony B. Morland
    [J]. Brain Structure and Function, 2021, 226 : 2855 - 2867
  • [7] Assessing functional reorganization in visual cortex with simulated retinal lesions
    Brown, Holly D. H.
    Gouws, Andre D.
    Vernon, Richard J. W.
    Lawrence, Samuel J. D.
    Donnelly, Gemma
    Gill, Lorraine
    Gale, Richard P.
    Baseler, Heidi A.
    Morland, Antony B.
    [J]. BRAIN STRUCTURE & FUNCTION, 2021, 226 (09): : 2855 - 2867
  • [8] Serial Functional Imaging Poststroke Reveals Visual Cortex Reorganization
    Brodtmann, Amy
    Puce, Aina
    Darby, David
    Donnan, Geoffrey
    [J]. NEUROREHABILITATION AND NEURAL REPAIR, 2009, 23 (02) : 150 - 159
  • [9] RETINAL-DETACHMENT INDUCES MASSIVE IMMEDIATE REORGANIZATION IN VISUAL-CORTEX
    SCHMID, LM
    ROSA, MGP
    CALFORD, MB
    [J]. NEUROREPORT, 1995, 6 (09) : 1349 - 1353
  • [10] REORGANIZATION PROCESSES IN THE VISUAL-CORTEX ALSO DEPEND ON VISUAL EXPERIENCE IN THE ADULT CAT
    MILLERET, C
    BUSER, P
    [J]. PROGRESS IN BRAIN RESEARCH, 1993, 95 : 257 - 269