Massive restructuring of neuronal circuits during functional reorganization of adult visual cortex

被引：0
|
作者：
Tara Keck
Thomas D Mrsic-Flogel
Miguel Vaz Afonso
Ulf T Eysel
Tobias Bonhoeffer
Mark Hübener
机构：
[1] Max Planck Institute of Neurobiology,Department of Neurophysiology
[2] Am Klopfersptiz 18,undefined
[3] Ruhr University Bochum,undefined
[4] Present address: Department of Physiology,undefined
[5] University College London,undefined
[6] 21 University Street,undefined
[7] London,undefined
[8] WC1E 6JJ,undefined
[9] UK.,undefined
来源：
Nature Neuroscience | 2008年 / 11卷
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摘要：
Following a retinal lesion, it is known that extensive topographical remapping occurs in visual cortex. To examine the dynamics of this plasticity, Keck et al. combined chronic intrinsic and two-photon imaging to follow both the functional and structural modifications of the affected cortical region. They observed close to a complete turnover of spines on the functionally relevant cells, suggesting that a massive rewiring had occurred, producing new circuits.
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页码：1162 / 1167
页数：5
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