Nanoparticles for super-resolution microscopy and single-molecule tracking

被引:0
|
作者
Dayong Jin
Peng Xi
Baoming Wang
Le Zhang
Jörg Enderlein
Antoine M. van Oijen
机构
[1] University of Technology Sydney,Institute for Biomedical Materials & Devices (IBMD), Faculty of Science
[2] College of Engineering,Department of Biomedical Engineering
[3] Peking University,Third Institute of Physics
[4] University of Göttingen,School of Chemistry
[5] University of Wollongong and Illawarra Health and Medical Research Institute,undefined
来源
Nature Methods | 2018年 / 15卷
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摘要
We review the use of luminescent nanoparticles in super-resolution imaging and single-molecule tracking, and showcase novel approaches to super-resolution imaging that leverage the brightness, stability, and unique optical-switching properties of these nanoparticles. We also discuss the challenges associated with their use in biological systems, including intracellular delivery and molecular targeting. In doing so, we hope to provide practical guidance for biologists and continue to bridge the fields of super-resolution imaging and nanoparticle engineering to support their mutual advancement.
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页码:415 / 423
页数:8
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