Identification of multiple risk variants for ankylosing spondylitis through high-density genotyping of immune-related loci

被引：0

作者：

机构：

[1] University of Queensland Diamantina Institute,Department of Rheumatology

[2] Translational Research Institute,Department of Medicine, Division of Rheumatology

[3] National Institute for Health Research (NIHR) Oxford Musculoskeletal Biomedical Research Unit,Department of Medicine/Rheumatology

[4] Nuffield Orthopaedic Centre,Division of Rheumatology

[5] Hanyang University Hospital for Rheumatic Diseases,Division of Medicine

[6] Eulji University Hospital,Department of Medical Genetics

[7] Cedars-Sinai Medical Center,Department of Immunology

[8] National Institute of Arthritis and Musculoskeletal and Skin Diseases,Department of Rheumatology

[9] US National Institutes of Health,Department of Rheumatology and Immunology

[10] Rheumatology and Clinical Immunogenetics,Department of Rheumatology

[11] University of Texas Health Science Center at Houston,Department of Rheumatology

[12] Institut Cochin,Department of Medicine

[13] Université Paris–Descartes,Division of Rheumatology

[14] Centre National de Recherche Scientifique (CNRS) Unité Mixte de Recherhce (UMR) 8104,Rheumatology Department

[15] Institut National de la Santé et de la Recherche Médicale (INSERM) U1016,Rheumatology Department

[16] Ambroise Paré Hospital,Rheumatology Department

[17] Assistance Publique–Hôpitaux de Paris,Department of Immunology

[18] Versailles-Saint-Quentin en Yvelines University,Department of Rheumatology

[19] University Hospital North Norway,Department of Medicine

[20] Royal Darwin Hospital,Division of Rheumatology

[21] University of Oslo and Oslo University Hospital,Department of Medicine

[22] Oslo University Hospital,Department of Medical Microbiology and Infection Control

[23] University Hospital Oslo,Department of Rheumatology

[24] Centre for Vascular Prevention,Department of Medicine, Division of Allergy

[25] Danube-University Krems,Division of Rheumatology

[26] Diabetes Prevention Unit,Department of Laboratory Medicine

[27] National Institute for Health and Welfare,Department of Immunology and Transfusion Medicine

[28] King Abdulaziz University,undefined

[29] Paijat-Hame Central Hospital,undefined

[30] Shanghai Changzheng Hospital,undefined

[31] Second Military Medical University,undefined

[32] Ghent University Hospital,undefined

[33] Hospital General de México,undefined

[34] Faculty of Medicine,undefined

[35] Universidad Nacional Autónoma de México,undefined

[36] Dunedin School of Medicine,undefined

[37] University of Otago,undefined

[38] Toronto Western Hospital,undefined

[39] Queensland Institute of Medical Research,undefined

[40] Royal Brisbane Hospital,undefined

[41] Hospital Puerta de Hierro,undefined

[42] Complejo Hospitalario La Coruña,undefined

[43] Instituto de Investigación Biomédica A Coruña (INIBIC),undefined

[44] Hospital Marqués de Valcecilla,undefined

[45] Instituto de Formación e Investigación Marqués de Valcecillas (IFIMAV),undefined

[46] Asturias Central University Hospital,undefined

[47] Fundación Renal Iñigo Alvarez de Toledo,undefined

[48] Wellcome Trust Sanger Institute,undefined

[49] Wellcome Trust Centre for Human Genetics,undefined

[50] University of Oxford,undefined

来源：

Nature Genetics | 2013年 / 45卷

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摘要：

Matthew Brown and colleagues identify multiple susceptibility variants for ankylosing spondylitis through an association study based on high-density genotyping of immune-related loci. Their findings implicate numerous biological pathways in the pathogenesis of this disease and highlight shared risk factors with other autoimmune diseases.

引用

页码：730 / 738

页数：8

共 46 条

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