Gene Expression Profiles of ABC Transporters and Cytochrome P450 3A in Caco-2 and Human Colorectal Cancer Cell Lines

被引：0
|
作者：
Tsutomu Nakamura
Toshiyuki Sakaeda
Nobuko Ohmoto
Yuka Moriya
Chiho Komoto
Toshiro Shirakawa
Akinobu Gotoh
Masafumi Matsuo
Katsuhiko Okumura
机构：
[1] Kobe University,Department of Hospital Pharmacy, School of Medicine
[2] Kobe University,Department of Urology, School of Medicine
[3] Kobe University,Departments of Clinical Genetics and International Center for Medical Research, School of Medicine
来源：
Pharmaceutical Research | 2003年 / 20卷
关键词：
MDR1; multidrug resistance-associated protein (MRP); villin; screening model;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Purpose. The mRNA levels of MDR1 (P-glycoprotein), multidrug resistance-associated proteins (MRP1, MRP2), cytochrome P450 3A (CYP3A) and villin in human colorectal cell lines (HCT-15, LoVo, DLD-1, HCT-116 and SW620) were quantitatively compared with those in Caco-2 cells.
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页码：324 / 327
页数：3
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