Pregnenolone activates CLIP-170 to promote microtubule growth and cell migration

被引:0
|
作者
Jui-Hsia Weng
Ming-Ren Liang
Chien-Han Chen
Sok-Keng Tong
Tzu-Chiao Huang
Sue-Ping Lee
Yet-Ran Chen
Chao-Tsen Chen
Bon-chu Chung
机构
[1] Institute of Biochemistry and Molecular Biology,Department of Chemistry
[2] National Yang-Ming University,undefined
[3] Institute of Molecular Biology,undefined
[4] Academia Sinica,undefined
[5] National Taiwan University,undefined
[6] Agricultural Biotechnology Research Center,undefined
[7] Academia Sinica,undefined
来源
Nature Chemical Biology | 2013年 / 9卷
关键词
D O I
暂无
中图分类号
学科分类号
摘要
The neurosteroid pregnenolone binds the microtubule plus-end tracking protein CLIP-170 to promote microtubule polymerization and cell migration.[graphic not available: see fulltext]
引用
收藏
页码:636 / 642
页数:6
相关论文
共 50 条
  • [31] Evidence that CLIP-170 and EB1 track microtubule plus ends by similar but distinct mechanisms
    Folker, ES
    Askham, J
    Morrison, EE
    Goodson, HV
    MOLECULAR BIOLOGY OF THE CELL, 2004, 15 : 237A - 237A
  • [32] CLIP-170 tethers kinetochores to microtubule plus ends against poleward force by dynein for stable kinetochore-microtubule attachment
    Amin, Mohammed Abdullahel
    Kobayashi, Kinue
    Tanaka, Kozo
    FEBS LETTERS, 2015, 589 (19) : 2739 - 2746
  • [33] Cell cycle control of kinesin-mediated transport of Bik1 (CLIP-170) regulates microtubule stability and dynein activation
    Carvalho, P
    Gupta, ML
    Hoyt, MA
    Pellman, D
    DEVELOPMENTAL CELL, 2004, 6 (06) : 815 - 829
  • [34] Structural basis of microtubule plus end tracking by XMAP215, CLIP-170, and EB1
    Slep, Kevin C.
    Vale, Ronald D.
    MOLECULAR CELL, 2007, 27 (06) : 976 - 991
  • [35] AMPK regulates cell shape of cardiomyocytes by modulating turnover of microtubules through CLIP-170
    Yashirogi, Shohei
    Nagao, Takemasa
    Nishida, Yuya
    Takahashi, Yusuke
    Qaqorh, Tasneem
    Yazawa, Issei
    Katayama, Toru
    Kioka, Hidetaka
    Matsui, Tsubasa S.
    Saito, Shigeyoshi
    Masumura, Yuki
    Tsukamoto, Osamu
    Kato, Hisakazu
    Ueda, Hiromichi
    Yamaguchi, Osamu
    Yashiro, Kenta
    Yamazaki, Satoru
    Takashima, Seiji
    Shintani, Yasunori
    EMBO REPORTS, 2021, 22 (01)
  • [36] AMPK regulates cell shape of cardiomyocytes by modulating turnover of microtubules through CLIP-170
    Yashirogi S.
    Nagao T.
    Nishida Y.
    Takahashi Y.
    Qaqorh T.
    Yazawa I.
    Katayama T.
    Kioka H.
    Matsui T.S.
    Saito S.
    Masumura Y.
    Tsukamoto O.
    Kato H.
    Ueda H.
    Yamaguchi O.
    Yashiro K.
    Yamazaki S.
    Takashima S.
    Shintani Y.
    The EMBO Reports, 2021, 22 (1):
  • [37] Ninein is essential for apico-basal microtubule formation and CLIP-170 facilitates its redeployment to non-centrosomal microtubule organizing centres
    Goldspink, Deborah A.
    Rookyard, Chris
    Tyrrell, Benjamin J.
    Gadsby, Jonathan
    Perkins, James
    Lund, Elizabeth K.
    Galjart, Niels
    Thomas, Paul
    Wileman, Tom
    Mogensen, Mette M.
    OPEN BIOLOGY, 2017, 7 (02):
  • [38] Microtubule plus end associated CLIP-170 initiates HSV-1 retrograde transport in primary human cells
    Jovasevic, Vladimir
    Naghavi, Mojgan H.
    Walsh, Derek
    JOURNAL OF CELL BIOLOGY, 2015, 211 (02): : 323 - 337
  • [39] Ubiquitination of CLIP-170 family protein restrains polarized growth upon DNA replication stress
    Wang, Xi
    Zheng, Fan
    Yi, Yuan-yuan
    Wang, Gao-yuan
    Hong, Li-xin
    McCollum, Dannel
    Fu, Chuanhai
    Wang, Yamei
    Jin, Quan-wen
    NATURE COMMUNICATIONS, 2022, 13 (01)
  • [40] Overexpression of the microtubule-binding protein CLIP-170 induces a plus TIP network superstructure consistent with a biomolecular condensate
    Wu, Yueh-Fu O.
    Bryant, Annamarie T.
    Nelson, Nora T.
    Madey, Alexander G.
    Fernandes, Gail F.
    Goodson, Holly V.
    PLOS ONE, 2021, 16 (12):